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Molecular Diagnostics & Diagnostic Imaging

  • Ubiquitin and SUMO conjugation as biomarkers of acute myeloid leukemias response to chemotherapies
    Open Access
    Ubiquitin and SUMO conjugation as biomarkers of acute myeloid leukemias response to chemotherapies

    Pierre Gâtel, Frédérique Brockly, Christelle Reynes, Manuela Pastore, Yosr Hicheri, Guillaume Cartron, Marc Piechaczyk, Guillaume Bossis

    Pierre Gâtel ... Guillaume Bossis

    Published 17 April 2020

    This study describes the identification of a new class of biomarkers of cancer response to therapies based on protein modification by ubiquitin and SUMO and developed tools to validate them in acute myeloid leukemia patient samples.

  • Reference-free transcriptome exploration reveals novel RNAs for prostate cancer diagnosis
    Open Access
    Reference-free transcriptome exploration reveals novel RNAs for prostate cancer diagnosis

    Marina Pinskaya, Zohra Saci, Mélina Gallopin, Marc Gabriel, Ha TN Nguyen, Virginie Firlej, Marc Descrimes, Audrey Rapinat, David Gentien, Alexandre de la Taille, Arturo Londoño-Vallejo, Yves Allory, Daniel Gautheret, Antonin Morillon

    Marina Pinskaya ... Antonin Morillon

    Published 15 November 2019

    A reference-free computational workflow for the discovery of unannotated RNA biomarkers retrieves novel noncoding RNAs with high potential for prostate cancer diagnosis.

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