[HTML][HTML] Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies

J Jing, Z Wu, J Wang, G Luo, H Lin, Y Fan… - Signal Transduction and …, 2023 - nature.com
The past decade has seen significant advances in our understanding of Hedgehog (HH)
signaling pathway in various biological events. HH signaling pathway exerts its biological …

Ulk4 promotes Shh signaling by regulating Stk36 ciliary localization and Gli2 phosphorylation

M Zhou, Y Han, J Jiang - Elife, 2023 - elifesciences.org
Abstract The Hedgehog (Hh) family of secreted proteins governs embryonic development
and adult tissue homeostasis through the Gli family of transcription factors. Gli is thought to …

[HTML][HTML] Beyond cyclopamine: Targeting Hedgehog signaling for cancer intervention

BT Baby, AM Kulkarni, PKR Gayam… - Archives of Biochemistry …, 2024 - Elsevier
Hedgehog (Hh) signaling plays a significant role in embryogenesis and several
physiological processes, such as wound healing and organ homeostasis. In a pathological …