[HTML][HTML] Temporal dynamics of muscle mitochondrial uncoupling-induced integrated stress response and ferroptosis defense

C Igual Gil, A Löser, K Lossow, M Schwarz… - Frontiers in …, 2023 - frontiersin.org
Mitochondria play multifaceted roles in cellular function, and impairments across domains of
mitochondrial biology are known to promote cellular integrated stress response (ISR) …

[HTML][HTML] Beneficial Effects of Low-Grade Mitochondrial Stress on Metabolic Diseases and Aging

SH Min, GM Kang, JW Park, MS Kim - Yonsei Medical Journal, 2024 - ncbi.nlm.nih.gov
Mitochondria function as platforms for bioenergetics, nutrient metabolism, intracellular
signaling, innate immunity regulators, and modulators of stem cell activity. Thus, the decline …

[HTML][HTML] Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle

J Masania, P Wijten, S Keipert, M Ost, S Klaus… - Redox Biology, 2023 - Elsevier
Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a
healthy aging phenotype with increased longevity and resistance to impaired metabolic …