Traumatic injuries of the central nervous system (CNS) affect millions of people worldwide,
and they can lead to severely damaging consequences such as permanent disability and …

The chemokine CXC-ligand 13 (CXCL13) is a major B cell chemoattractant to B cell follicles
in secondary lymphoid organs (SLO) that proposedly recruits B cells to the cerebrospinal …

Most antibodies produced in the body are of the IgA class. The dominant cell population
producing them are plasma cells within the lamina propria of the gastrointestinal tract, but …

Background Ischemic stroke is a leading cause of mortality worldwide, largely due to the
inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing …

The meninges are important for brain development and pathology. Using single-cell RNA
sequencing, we have generated the first comprehensive transcriptional atlas of neonatal …

Since its recent discovery, the meningeal lymphatic system has reshaped our understanding
of central nervous system (CNS) fluid exchange, waste clearance, immune cell trafficking …

Monocytes and lymphocytes elicit crucial activities for the regenerative processes after
various types of injury. The survival of neurons exposed to mechanical and oxidative stress …

Simple Summary The tumor immune microenvironment is an important area of tumor
research. Tertiary lymphoid structures, as a specific component of this, have recently begun …

Background Immune cells play crucial roles after spinal cord injury (SCI). However,
incomplete knowledge of immune contributions to injury and repair hinders development of …

Hereditary spastic paraplegia (HSP) is a group of genetic motor neuron diseases resulting
from length-dependent axonal degeneration of the corticospinal upper motor neurons. Due …