Hepsin: a multifunctional transmembrane serine protease in pathobiology

S Li, L Wang, S Sun, Q Wu - The FEBS Journal, 2021 - Wiley Online Library
Cell membrane‐bound serine proteases are important in the maintenance of physiological
homeostasis. Hepsin is a type II transmembrane serine protease highly expressed in the …

[HTML][HTML] S protein, ACE2 and host cell proteases in SARS-CoV-2 cell entry and infectivity; is soluble ACE2 a two blade sword? A narrative review

R Nejat, MF Torshizi, DJ Najafi - Vaccines, 2023 - mdpi.com
Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …

[HTML][HTML] Interactions of ferritin with scavenger receptor class A members

B Yu, C Cheng, Y Wu, L Guo, D Kong, Z Zhang… - Journal of Biological …, 2020 - ASBMB
Scavenger receptors are a superfamily of membrane-bound receptors that recognize both
self and nonself targets. Scavenger receptor class A (SR-A) has five known members …

[HTML][HTML] Salivary microbiome changes distinguish response to chemoradiotherapy in patients with oral cancer

MC Medeiros, S The, E Bellile, N Russo, L Schmitd… - Microbiome, 2023 - Springer
Background Oral squamous cell carcinoma (SCC) is associated with oral microbial
dysbiosis. In this unique study, we compared pre-to post-treatment salivary microbiome in …

[HTML][HTML] Dissecting the extracellular complexity of neuromuscular junction organizers

SR Guarino, A Canciani, F Forneris - Frontiers in molecular …, 2020 - frontiersin.org
Synapse formation is a very elaborate process dependent upon accurate coordination of pre
and post-synaptic specialization, requiring multiple steps and a variety of receptors and …

[HTML][HTML] New Functions of Intracellular LOXL2: Modulation of RNA-Binding Proteins

P Eraso, MJ Mazón, V Jiménez, P Pizarro-García… - Molecules, 2023 - mdpi.com
Lysyl oxidase-like 2 (LOXL2) was initially described as an extracellular enzyme involved in
extracellular matrix remodeling. Nevertheless, numerous recent reports have implicated …

[HTML][HTML] Why the lower reported prevalence of asthma in patients diagnosed with COVID-19 validates repurposing EDTA solutions to prevent and manage treat COVID …

DP Cashman - Medical Hypotheses, 2020 - Elsevier
There currently is no specific antiviral drug or a vaccine for SARS-CoV-2/COVID-19
infections; now exceeding 10,300,000 infections worldwide. In the absence of animal …

[HTML][HTML] Polymer adhesin domains in gram-positive cell surface proteins

MA Järvå, H Hirt, GM Dunny… - Frontiers in Microbiology, 2020 - frontiersin.org
Surface proteins in Gram-positive bacteria are often involved in biofilm formation, host-cell
interactions, and surface attachment. Here we review a protein module found in surface …

[HTML][HTML] LOXL2 in Cancer: A Two-Decade Perspective

A Cano, P Eraso, MJ Mazón, F Portillo - International Journal of Molecular …, 2023 - mdpi.com
Lysyl Oxidase Like 2 (LOXL2) belongs to the lysyl oxidase (LOX) family, which comprises
five lysine tyrosylquinone (LTQ)-dependent copper amine oxidases in humans. In 2003 …

[HTML][HTML] Genome-Wide Comparative Analysis of SRCR Gene Superfamily in Invertebrates Reveals Massive and Independent Gene Expansions in the Sponge and …

Z Peng, W Zhang, H Fu, Y Li, C Zhang, J Li… - International Journal of …, 2024 - mdpi.com
Without general adaptative immunity, invertebrates evolved a vast number of heterogeneous
non-self recognition strategies. One of those well-known adaptations is the expansion of the …