[HTML][HTML] Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

A Cruz Camacho, D Alfandari, E Kozela… - PLoS …, 2023 - journals.plos.org
Extracellular vesicles (EVs) provide a central mechanism of cell–cell communication. While
EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of …

[HTML][HTML] Current understanding of extracellular vesicle homing/tropism

MJ Edelmann, PE Kima - Zoonoses (Burlington, Mass.), 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are membrane-enclosed packets released from cells that can
transfer bioactive molecules from cell to cell without direct contact with the target cells. This …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

[HTML][HTML] Modulation of host immune response during leishmania infantum natural infection: A whole-transcriptome analysis of the popliteal lymph nodes in dogs

CR Sanz, G Miró, N Sevane… - Frontiers in …, 2022 - frontiersin.org
Leishmania infantum, the etiological agent of canine leishmaniosis (CanL) in Europe, was
responsible of the largest outbreak of human leishmaniosis in Spain. The parasite infects …

[HTML][HTML] Characterization and proteomic analysis of plasma EVs recovered from healthy and diseased dogs with canine leishmaniosis

S Esteves, C Lima, I Costa, H Osório… - International Journal of …, 2023 - mdpi.com
Dogs are highly valued companions and work animals that are susceptible to many life-
threatening conditions such as canine leishmaniosis (CanL). Plasma-derived extracellular …

Transforming parasites into their own foes: parasitic extracellular vesicles as a vaccine platform

D Alfandari, S Cadury, MI Morandi… - Trends in …, 2023 - cell.com
Parasitic diseases continue to afflict millions of people globally. However, traditional vaccine
development strategies are often difficult to apply to parasites, leaving an immense unmet …

[HTML][HTML] Intravacuolar pathogens hijack host extracellular vesicle biogenesis to secrete virulence factors

A Gioseffi, MJ Edelmann, PE Kima - Frontiers in Immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) have garnered significant interest in recent years due to their
contributions to cell-to-cell communication and disease processes. EVs are composed of a …

[HTML][HTML] Extracellular vesicles secreted by Echinococcus multilocularis: important players in angiogenesis promotion

C Liu, J Cao, H Zhang, MC Field, J Yin - Microbes and Infection, 2023 - Elsevier
The involvement of Echinococcus multilocularis, and other parasitic helminths, in regulating
host physiology is well recognized, but molecular mechanisms remain unclear. Extracellular …

Leishmania survives by exporting miR-146a from infected to resident cells to subjugate inflammation

S Ganguly, B Ghoshal, I Banerji… - Life Science …, 2022 - life-science-alliance.org
Leishmania donovani, the causative agent of visceral leishmaniasis, infects and resides
within tissue macrophage cells. It is not clear how the parasite infected cells crosstalk with …

[HTML][HTML] The role of extracellular vesicles from human macrophages on host-pathogen interaction

LA Arteaga-Blanco, DC Bou-Habib - International Journal of Molecular …, 2021 - mdpi.com
The nano-sized membrane enclosed extracellular vesicles (EVs) released by virtually all cell
types play an essential role in intercellular communication via delivering bio-molecules …