Ferrous iron-dependent pharmacology
RL Gonciarz, EA Collisson, AR Renslo - Trends in pharmacological …, 2021 - cell.com
The recent emergence of oxidation state selective probes of cellular iron has produced a
more nuanced understanding of how cells utilize this crucial nutrient to empower enzyme …
more nuanced understanding of how cells utilize this crucial nutrient to empower enzyme …
Emerging role of ferrous iron in bacterial growth and host–pathogen interaction: New tools for chemical (micro) biology and antibacterial therapy
RL Gonciarz, AR Renslo - Current opinion in chemical biology, 2021 - Elsevier
Chemical tools capable of detecting ferrous iron with oxidation-state specificity have only
recently become available. Coincident with this development in chemical biology has been …
recently become available. Coincident with this development in chemical biology has been …
Epigenomic regulation by labile iron
V Camarena, TC Huff, G Wang - Free Radical Biology and Medicine, 2021 - Elsevier
Iron is an essential micronutrient metal for cellular functions but can generate highly reactive
oxygen species resulting in oxidative damage. For these reasons its uptake and metabolism …
oxygen species resulting in oxidative damage. For these reasons its uptake and metabolism …
[PDF][PDF] Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types
Cyclic adenosine monophosphate (cAMP) is a generic signaling molecule that, through
precise control of its signaling dynamics, exerts distinct cellular effects. Consequently …
precise control of its signaling dynamics, exerts distinct cellular effects. Consequently …
SAMD1 distribution patterns in mouse atherosclerosis models suggest roles in LDL retention, antigen presentation, and cell phenotype modulation
B Campbell, P Bourassa, R Aiello - Biorxiv, 2021 - biorxiv.org
The theory that lesions formed by retention of circulating LDL can then progress to
complicated atherosclerotic lesions has been a subject of debate, as has the mechanism of …
complicated atherosclerotic lesions has been a subject of debate, as has the mechanism of …
Ablation of SAMD1 in mice causes failure of angiogenesis, embryonic lethality
B Campbell, S Engle, T Ozolins, P Bourassa, R Aiello - bioRxiv, 2022 - biorxiv.org
Pathological retention of LDL in the intima is involved in atherosclerosis, although the
retention mechanisms are not well-understood. Previously, we reported Sterile Alpha Motif …
retention mechanisms are not well-understood. Previously, we reported Sterile Alpha Motif …