CRISPR/Cas‐based precision genome editing via microhomology‐mediated end joining
T Van Vu, D Thi Hai Doan, J Kim… - Plant Biotechnology …, 2021 - Wiley Online Library
Gene editing and/or allele introgression with absolute precision and control appear to be the
ultimate goals of genetic engineering. Precision genome editing in plants has been …
ultimate goals of genetic engineering. Precision genome editing in plants has been …
Editing of DNA methylation using CRISPR/Cas9 and a ssDNA template in human cells
S Katayama, M Andou - Biochemical and Biophysical Research …, 2021 - Elsevier
Programmable DNA methylation is required for understanding of transcriptional regulation
and elucidating gene functions. We previously reported that MMEJ-based promoter …
and elucidating gene functions. We previously reported that MMEJ-based promoter …
Engineering of Zinc Finger Nucleases Through Structural Modeling Improves Genome Editing Efficiency in Cells
S Katayama, M Watanabe, Y Kato, W Nomura… - Advanced …, 2024 - Wiley Online Library
Genome Editing is widely used in biomedical research and medicine. Zinc finger nucleases
(ZFNs) are smaller in size than transcription activator‐like effector (TALE) nucleases …
(ZFNs) are smaller in size than transcription activator‐like effector (TALE) nucleases …
A CRISPR/Cas9‐based method for targeted DNA methylation enables cancer initiation in B lymphocytes
S Katayama, K Shiraishi, N Gorai… - Advanced …, 2021 - Wiley Online Library
Targeted DNA methylation is important for understanding transcriptional modulation and
epigenetic diseases. Although CRISPR‐Cas9 has potential for this purpose, it has not yet …
epigenetic diseases. Although CRISPR‐Cas9 has potential for this purpose, it has not yet …
[HTML][HTML] REMOVER-PITCh: microhomology-assisted long-range gene replacement with highly multiplexed CRISPR-Cas9
S Matsuzaki, T Sakuma, T Yamamoto - In Vitro Cellular & Developmental …, 2024 - Springer
A variety of CRISPR-Cas9-based gene editing technologies have been developed,
including gene insertion and gene replacement, and applied to the study and treatment of …
including gene insertion and gene replacement, and applied to the study and treatment of …
A more efficient method for generating glioblastoma-multiforme model in mice using genome editing technology
N Ohtsu, S Katayama - Biochemical and Biophysical Research …, 2024 - Elsevier
The elucidation of the properties of malignant glioma and development of therapeutic
methods require glioblastoma-multiforme mice model with characteristics such as …
methods require glioblastoma-multiforme mice model with characteristics such as …
遺伝子ノックイン方法, 遺伝子ノックイン細胞作製方法, 遺伝子ノックイン細胞, がん化リスク評価方法, がん細胞製造方法, 及びこれらに用いるためのキット
翔太片山 - 2021 - Google Patents
WO2021171688A1 - 遺伝子ノックイン方法,遺伝子ノックイン細胞作製方法,遺伝子ノックイン細胞,がん
化リスク評価方法,がん細胞製造方法,及びこれらに用いるためのキット - Google Patents …
化リスク評価方法,がん細胞製造方法,及びこれらに用いるためのキット - Google Patents …