Persistent cancer cells are the discrete and usually undetected cells that survive cancer drug
treatment and constitute a major cause of treatment failure. These cells are characterized by …

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Epithelial cell death is highly prevalent during development and tissue homeostasis. While
we have a rather good understanding of the molecular regulators of programmed cell death …

Mass cytometry (MC) is a recent technology that pairs plasma-based ionization of cells in
suspension with time-of-flight (TOF) mass spectrometry to sensitively quantify the single-cell …

Extrinsic apoptosis relies on TNF-family receptor activation by immune cells or receptor-
activating drugs. Here, we monitored cell cycle progression at a resolution of minutes to …

Cisatracurium besilate is the most commonly used non-depolarizing muscle relaxant in
general anesthesia and in intensive care units. Studies have indicated that the proliferation …

Hematopoietic stem and progenitor cell (HSPC) transplantation is an essential therapy for
hematological conditions, but finer definitions of human HSPC subsets with associated …

TRAIL has been demonstrated to play a critical role in the apoptosis of colorectal cancer
(CRC) cells, but drug resistance markedly restricts its therapeutic effects. Objectives: This …

Clinical observations suggest that identifying novel curative and preventive approaches by
targeting the tumor cells without affecting the normal cells is appreciable. Diosgenin (DG) is …

The tumour necrosis factor superfamily (TNFSF) plays critical roles in tumour apoptosis,
tissue morphogenesis and lineage determination. TNFSF10 (TRAIL or Apol‐2) belongs to …