Cellular functions of eukaryotic RNA helicases and their links to human diseases
KE Bohnsack, S Yi, S Venus, E Jankowsky… - … Reviews Molecular Cell …, 2023 - nature.com
RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …
Regulation of the multisubunit CCR4-NOT deadenylase in the initiation of mRNA degradation
The conserved CCR4-NOT complex initiates the decay of mRNAs by catalyzing the
shortening of their poly (A) tails in a process known as deadenylation. Recent studies have …
shortening of their poly (A) tails in a process known as deadenylation. Recent studies have …
4E-T-bound mRNAs are stored in a silenced and deadenylated form
F Räsch, R Weber, E Izaurralde… - Genes & …, 2020 - genesdev.cshlp.org
Human 4E-T is an eIF4E-binding protein (4E-BP) present in processing (P)-bodies that
represses translation and regulates decay of mRNAs destabilized by AU-rich elements and …
represses translation and regulates decay of mRNAs destabilized by AU-rich elements and …
[HTML][HTML] Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation
Background Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) is known to
associate with cytoplasmic polyadenylation elements (CPEs) located in the 3′ untranslated …
associate with cytoplasmic polyadenylation elements (CPEs) located in the 3′ untranslated …
[HTML][HTML] Regulation by the RNA-binding protein Unkempt at its effector interface
How RNA-binding proteins (RBPs) convey regulatory instructions to the core effectors of
RNA processing is unclear. Here, we document the existence and functions of a multivalent …
RNA processing is unclear. Here, we document the existence and functions of a multivalent …
[HTML][HTML] Evolutionary and Expression Analysis of MOV10 and MOV10L1 Reveals Their Origin, Duplication and Divergence
S Yang, X Zhang, X Li, X Yin, L Teng, G Ji… - International journal of …, 2022 - mdpi.com
MOV10 and MOV10L1 both encode ATP-dependent RNA helicases. In mammals, MOV10
and MOV10L1 participate in various kinds of biological contexts, such as defense of RNA …
and MOV10L1 participate in various kinds of biological contexts, such as defense of RNA …
[HTML][HTML] Comparative Transcriptomic Analysis Reveals Adaptive Traits in Antarctic Scallop Adamussium colbecki
Antarctica is the most extreme continent of Earth, with strong winds, freezing temperatures
on land, and ocean temperatures constantly below 0° C. Nonetheless, the Antarctic Ocean is …
on land, and ocean temperatures constantly below 0° C. Nonetheless, the Antarctic Ocean is …
[HTML][HTML] Transcriptomic analysis of laying hens revealed the role of aging-related genes during forced molting
T Zhang, Y Chen, J Wen, Y Jia, L Wang, X Lv, W Yang… - Genes, 2021 - mdpi.com
Molting in birds provides us with an ideal genetic model for understanding aging and
rejuvenation since birds present younger characteristics for reproduction and appearance …
rejuvenation since birds present younger characteristics for reproduction and appearance …
Spatial proteomic approach to characterize skeletal muscle myofibers
KM Fomchenko, EM Walsh, X Yang… - Journal of proteome …, 2020 - ACS Publications
Skeletal muscle myofibers have differential protein expression resulting in functionally
distinct slow-and fast-twitch types. While certain protein classes are well-characterized, the …
distinct slow-and fast-twitch types. While certain protein classes are well-characterized, the …
[HTML][HTML] Genomics of Dwarfism in Italian local chicken breeds
The identification of the dwarf phenotype in chicken is based on body weight, height, and
shank length, leaving the differentiation between dwarf and small breeds ambiguous. The …
shank length, leaving the differentiation between dwarf and small breeds ambiguous. The …