The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle
Eukaryotic chromosome segregation relies upon specific connections from DNA to the
microtubule-based spindle that forms at cell division. The chromosomal locus that directs …
microtubule-based spindle that forms at cell division. The chromosomal locus that directs …
Kinetochore assembly throughout the cell cycle
AP Navarro, IM Cheeseman - Seminars in cell & developmental biology, 2021 - Elsevier
The kinetochore plays an essential role in facilitating chromosome segregation during cell
division. This massive protein complex assembles onto the centromere of chromosomes and …
division. This massive protein complex assembles onto the centromere of chromosomes and …
The cysteine-rich domain in CENP-A chaperone Scm3HJURP ensures centromere targeting and kinetochore integrity
HD Folco, H Xiao, D Wheeler, H Feng… - Nucleic Acids …, 2024 - academic.oup.com
Centromeric chromatin plays a crucial role in kinetochore assembly and chromosome
segregation. Centromeres are specified through the loading of the histone H3 variant CENP …
segregation. Centromeres are specified through the loading of the histone H3 variant CENP …