User profiles for Zixin Qin

zixin qin

University of Macau
Verified email at connect.um.edu.mo
Cited by 183

[HTML][HTML] Crosstalks Between Gut Microbiota and Vibrio Cholerae

Z Qin, X Yang, G Chen, C Park, Z Liu - Frontiers in Cellular and …, 2020 - frontiersin.org
Vibrio cholerae, the causative agent of cholera, could proliferate in aquatic environment and
infect humans through contaminated food and water. Enormous microorganisms residing in …

Germline variation in BRCA1/2 is highly ethnic‐specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients

…, S Sinha, L Jiang, B Lu, X Wu, Z Qin… - … journal of cancer, 2019 - Wiley Online Library
BRCA1 and BRCA2 play essential roles in maintaining the genome stability. Pathogenic
germline mutations in these two genes disrupt their function, lead to genome instability and …

Human BRCA pathogenic variants were originated during recent human history

J Li, B Zhao, T Huang, Z Qin… - Life Science …, 2022 - life-science-alliance.org
BRCA1 and BRCA2 (BRCA) play essential roles in maintaining genome stability. BRCA
germline pathogenic variants increase cancer risk. However, the evolutionary origin of human …

Ethnic-specific BRCA1/2 variation within Asia population: evidence from over 78 000 cancer and 40 000 non-cancer cases of Indian, Chinese, Korean and Japanese …

…, BK Rajendran, M Guo, J Luo, Z Qin… - Journal of medical …, 2021 - jmg.bmj.com
Background Germline mutation in BRCA1 and BRCA2 (BRCA) is genetic predisposition for
breast and ovarian cancer. Identification of mutation carriers is a critical step to prevent and …

[HTML][HTML] CBS-derived H2S facilitates host colonization of Vibrio cholerae by promoting the iron-dependent catalase activity of KatB

Y Ma, X Yang, H Wang, Z Qin, C Yi, C Shi, M Luo… - PLoS …, 2021 - journals.plos.org
Sensing and resisting oxidative stress is critical for Vibrio cholerae to survive in either the
aquatic environment or the gastrointestinal tract. Previous studies mainly focused on the …

Ethnic‐specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population

Z Qin, J Li, B Tam, S Sinha, B Zhao… - … journal of cancer, 2023 - Wiley Online Library
Pathogenic variation in BRCA1 and BRCA2 (BRCA) causes high risk of breast and ovarian
cancer, and BRCA variation data are important markers for BRCA‐related clinical cancer …

[HTML][HTML] Dps-dependent in vivo mutation enhances long-term host adaptation in Vibrio cholerae

M Luo, G Chen, C Yi, B Xue, X Yang, Y Ma, Z Qin… - PLoS …, 2023 - journals.plos.org
As one of the most successful pathogenic organisms, Vibrio cholerae (V. cholerae) has
evolved sophisticated regulatory mechanisms to overcome host stress. During long-term …

[HTML][HTML] Pathogenic variants in human DNA damage repair genes mostly arose in recent human history

B Zhao, J Li, S Sinha, Z Qin, SH Kou, F Xiao, H Lei… - BMC cancer, 2024 - Springer
Background Genome stability is maintained by the DNA damage repair (DDR) system composed
of multiple DNA repair pathways of hundreds of genes. Germline pathogenic variation (…

Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population

Z Qin, CN Kuok, H Dong, L Jiang, L Zhang… - Journal of medical …, 2021 - jmg.bmj.com
Background Pathogenic mutation in BRCA genes causes high cancer risk. Identifying the
mutation carriers plays key roles in preventing BRCA mutation-related cancer. Population …

[HTML][HTML] BRCA1 and BRCA2 Variation in Taiwanese General Population and the Cancer Cohort

J Chian, S Sinha, Z Qin, SM Wang - Frontiers in Molecular …, 2021 - frontiersin.org
BRCA1 and BRCA2 (BRCA) play essential roles in maintaining genome stability. Rapidly
evolving human BRCA generates oncogenic variants causing high cancer risk. BRCA …