Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
J Han, K Luby-Phelps, B Das, X Shu, Y Xia… - Science, 1998 - science.org
Mitogen stimulation of cytoskeletal changes and c-jun amino-terminal kinases is mediated
by Rac small guanine nucleotide-binding proteins. Vav, a guanosine diphosphate (GDP)–…
by Rac small guanine nucleotide-binding proteins. Vav, a guanosine diphosphate (GDP)–…
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism
…, J Kanellis, L Han, L Feng, YY Xia… - American Journal …, 2002 - journals.physiology.org
Hyperuricemia is associated with hypertension and vascular disease, but whether this represents
a causal relationship or an epiphenomenon remains unknown. We recently reported a …
a causal relationship or an epiphenomenon remains unknown. We recently reported a …
[HTML][HTML] LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in animal development
and has been linked to several high-risk cancers. Here, we report that LSD1 is an integral …
and has been linked to several high-risk cancers. Here, we report that LSD1 is an integral …
High performance thermoelectricity in earth‐abundant compounds based on natural mineral tetrahedrites
Thermoelectric materials can convert waste heat into electricity, potentially improving the
efficiency of energy usage in both industry and everyday life. Unfortunately, known good …
efficiency of energy usage in both industry and everyday life. Unfortunately, known good …
Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration
JZ Wang, YY Xia, I Grundke-Iqbal… - Journal of Alzheimer's …, 2013 - content.iospress.com
Microtubule associated protein tau is a phosphoprotein which potentially has 80 serine/threonine
and 5 tyrosine phosphorylation sites. Normal brain tau contains 2-3 moles of …
and 5 tyrosine phosphorylation sites. Normal brain tau contains 2-3 moles of …
Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones
Y Xia, ZY Yang, MJ Hour, SC Kuo, P Xia… - Bioorganic & medicinal …, 2001 - Elsevier
A series of 2′,3′,4′,6,7-substituted 2-aryl quinazolinones were synthesized and
evaluated for biological activity. Among them, 17 displayed significant growth inhibitory action …
evaluated for biological activity. Among them, 17 displayed significant growth inhibitory action …
Andrographolide attenuates inflammation by inhibition of NF-κB activation through covalent modification of reduced cysteine 62 of p50
YF Xia, BQ Ye, YD Li, JG Wang, XJ He… - The Journal of …, 2004 - journals.aai.org
NF-κB is a central transcriptional factor and a pleiotropic regulator of many genes involved
in immunological responses. During the screening of a plant extract library of traditional …
in immunological responses. During the screening of a plant extract library of traditional …
6-Alkylamino-and 2, 3-Dihydro-3 '-methoxy-2-phenyl-4-quinazolinones and related compounds: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization
MJ Hour, LJ Huang, SC Kuo, Y Xia… - Journal of medicinal …, 2000 - ACS Publications
As part of our continuing search for potential anticancer candidates among 2-phenyl-4-quinolones
and 2-phenyl-4-quinazolinones, two series of 6,7,2‘,3‘,4‘,5‘-substituted 2-phenyl-4-…
and 2-phenyl-4-quinazolinones, two series of 6,7,2‘,3‘,4‘,5‘-substituted 2-phenyl-4-…
Measuring efficiency in the hotel industry: A stochastic frontier approach
RI Anderson, M Fish, Y Xia, F Michello - International journal of hospitality …, 1999 - Elsevier
This study employs a stochastic frontier technique to estimate managerial efficiency levels
in the hotel industry. The only prior efficiency study in this sector employed a linear-…
in the hotel industry. The only prior efficiency study in this sector employed a linear-…
Effect of humic acid on plant growth, nutrient uptake, and postharvest life of gerbera
Humic acid (HA) might benefit plant growth by improving nutrient uptake and hormonal
effects. The effect of HA on growth, macro—and micronutrient contents, and postharvest life of …
effects. The effect of HA on growth, macro—and micronutrient contents, and postharvest life of …