Humanization of autoantigen
W Nishie, D Sawamura, M Goto, K Ito, A Shibaki… - Nature medicine, 2007 - nature.com
Transmissibility of characteristic lesions to experimental animals may help us understand the
pathomechanism of human autoimmune disease. Here we show that human autoimmune …
pathomechanism of human autoimmune disease. Here we show that human autoimmune …
[PDF][PDF] Hair follicle stem cells provide a functional niche for melanocyte stem cells
S Tanimura, Y Tadokoro, K Inomata, NT Binh, W Nishie… - Cell stem cell, 2011 - cell.com
In most stem cell systems, the organization of the stem cell niche and the anchoring matrix
required for stem cell maintenance are largely unknown. We report here that collagen XVII (…
required for stem cell maintenance are largely unknown. We report here that collagen XVII (…
[HTML][HTML] Autoantibody profile differentiates between inflammatory and noninflammatory bullous pemphigoid
Bullous pemphigoid (BP) is a major autoimmune blistering skin disorder, in which a majority
of the autoantibodies (autoAbs) target the juxtamembranous extracellular noncollagenous …
of the autoantibodies (autoAbs) target the juxtamembranous extracellular noncollagenous …
Update on the pathogenesis of bullous pemphigoid: an autoantibody-mediated blistering disease targeting collagen XVII
W Nishie - Journal of dermatological science, 2014 - Elsevier
Bullous pemphigoid (BP) is a common autoimmune blistering skin disorder that tends to
affect the elderly. Autoantibodies (autoAbs) from BP patients react with two hemidesmosomal …
affect the elderly. Autoantibodies (autoAbs) from BP patients react with two hemidesmosomal …
[HTML][HTML] Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid
K Tasanen, O Varpuluoma, W Nishie - Frontiers in immunology, 2019 - frontiersin.org
Bullous pemphigoid (BP) is an organ-specific autoantibody-mediated blistering skin disease
that mainly affects the elderly. Typical clinical features include the widespread blisters, often …
that mainly affects the elderly. Typical clinical features include the widespread blisters, often …
HLA-DQB1* 03: 01 as a biomarker for genetic susceptibility to bullous pemphigoid induced by DPP-4 inhibitors
…, T Ito, K Izumi, W Nishie… - The Journal of …, 2018 - pubmed.ncbi.nlm.nih.gov
… 2 , Wataru Nishie …
Bullous pemphigoid autoantibodies directly induce blister formation without complement activation
H Ujiie, T Sasaoka, K Izumi, W Nishie… - The Journal of …, 2014 - journals.aai.org
Complement activation and subsequent recruitment of inflammatory cells at the dermal/epidermal
junction are thought to be essential for blister formation in bullous pemphigoid (BP), an …
junction are thought to be essential for blister formation in bullous pemphigoid (BP), an …
Type XVII collagen coordinates proliferation in the interfollicular epidermis
10.7554/eLife.26635.001 Type XVII collagen (COL17) is a transmembrane protein located
at the epidermal basement membrane zone. COL17 deficiency results in premature hair …
at the epidermal basement membrane zone. COL17 deficiency results in premature hair …
Based ELISA for the Detection of Autoimmune Antibodies in Body Fluid The Case of Bullous Pemphigoid
CK Hsu, HY Huang, WR Chen, W Nishie… - Analytical …, 2014 - ACS Publications
Bullous pemphigoid (BP), a common autoimmune blistering disease, is increasing in incidence
and conveys a high mortality. Detection of autoantibodies targeting the noncollagenous …
and conveys a high mortality. Detection of autoantibodies targeting the noncollagenous …
[HTML][HTML] Granzyme B inhibition reduces disease severity in autoimmune blistering diseases
…, CT Turner, A Kasprick, C Tateishi, W Nishie… - Nature …, 2021 - nature.com
Pemphigoid diseases refer to a group of severe autoimmune skin blistering diseases
characterized by subepidermal blistering and loss of dermal-epidermal adhesion induced by …
characterized by subepidermal blistering and loss of dermal-epidermal adhesion induced by …