User profiles for W. F. Lenoir
 | Walter Frank Lenoir, PhDVerified email at utexas.edu Cited by 957 |
[HTML][HTML] Identifying chemogenetic interactions from CRISPR screens with drugZ
…, K Mascall, M McLaughlin, L Bertolet, WF Lenoir… - Genome medicine, 2019 - Springer
Background Chemogenetic profiling enables the identification of gene mutations that enhance
or suppress the activity of chemical compounds. This knowledge provides insights into …
or suppress the activity of chemical compounds. This knowledge provides insights into …
A network of human functional gene interactions from knockout fitness screens in cancer cells
Genetic interactions mediate the emergence of phenotype from genotype. The systematic
survey of genetic interactions in yeast showed that genes operating in the same biological …
survey of genetic interactions in yeast showed that genes operating in the same biological …
PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens
The adaptation of CRISPR/Cas9 systems for pooled library genetic knockout screens in
mammalian cells has substantially advanced the state of the art in human functional genomics. …
mammalian cells has substantially advanced the state of the art in human functional genomics. …
[HTML][HTML] Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells
WF Lenoir, M Morgado, PC DeWeirdt… - Nature …, 2021 - nature.com
CRISPR knockout fitness screens in cancer cell lines reveal many genes whose loss of
function causes cell death or loss of fitness or, more rarely, the opposite phenotype of faster …
function causes cell death or loss of fitness or, more rarely, the opposite phenotype of faster …
[HTML][HTML] The E. coli molecular phenotype under different growth conditions
Modern systems biology requires extensive, carefully curated measurements of cellular
components in response to different environmental conditions. While high-throughput methods …
components in response to different environmental conditions. While high-throughput methods …
DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress
Fanconi anemia (FA) is caused by defects in cellular responses to DNA crosslinking damage
and replication stress. Given the constant occurrence of endogenous DNA damage and …
and replication stress. Given the constant occurrence of endogenous DNA damage and …
Identifying chemogenetic interactions from CRISPR knockout screens with drugZ
…, K Mascall, M McLaughlin, L Bertolet, WF Lenoir… - Biorxiv, 2017 - biorxiv.org
Chemogenetic profiling enables the identification of gene mutations that enhance or
suppress the activity of chemical compounds. This knowledge provides insights into drug …
suppress the activity of chemical compounds. This knowledge provides insights into drug …
Microwave spectrum of molecular oxygen in the mesosphere
WB Lenoir - Journal of Geophysical Research, 1968 - Wiley Online Library
… Further increase of frequency brings both WF's deeper into the atmosphere as neither are
very intense at high altitudes. When the WF's reach •50-km polarization is no longer important, …
very intense at high altitudes. When the WF's reach •50-km polarization is no longer important, …
Hierarchical organization of the human cell from a cancer coessentiality network
Genetic interactions mediate the emergence of phenotype from genotype. Systematic survey
of genetic interactions in yeast showed that genes operating in the same biological process …
of genetic interactions in yeast showed that genes operating in the same biological process …
[PDF][PDF] Remote sounding of the upper atmosphere by microwave measurements.
WB Lenoir - 1965 - dspace.mit.edu
… The roles oflrzthe WF's have interchanged at AV'-=0.7 me where the 0” components are
most intense; Further increase in AVbrings both WF's deeper into the atmosphere (warmer …
most intense; Further increase in AVbrings both WF's deeper into the atmosphere (warmer …