Annexins: from structure to function
V Gerke, SE Moss - Physiological reviews, 2002 - journals.physiology.org
Annexins are Ca 2+ and phospholipid binding proteins forming an evolutionary conserved
multigene family with members of the family being expressed throughout animal and plant …
multigene family with members of the family being expressed throughout animal and plant …
[HTML][HTML] PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
Formation of the apical surface and lumen is a fundamental, yet poorly understood, step in
epithelial organ development. We show that PTEN localizes to the apical plasma membrane …
epithelial organ development. We show that PTEN localizes to the apical plasma membrane …
Annexin II is a major component of fusogenic endosomal vesicles.
N Emans, JP Gorvel, C Walter, V Gerke… - The Journal of cell …, 1993 - rupress.org
We have used an in vitro assay to follow the proteins transferred from a donor to an acceptor
upon fusion of early endosomes. The acceptor was a purified early endosomal fraction …
upon fusion of early endosomes. The acceptor was a purified early endosomal fraction …
Annexins: linking Ca2+ signalling to membrane dynamics
Eukaryotic cells contain various Ca 2+ -effector proteins that mediate cellular responses to
changes in intracellular Ca 2+ levels. A unique class of these proteins — annexins — can …
changes in intracellular Ca 2+ levels. A unique class of these proteins — annexins — can …
Annexins–unique membrane binding proteins with diverse functions
U Rescher, V Gerke - Journal of cell science, 2004 - journals.biologists.com
Annexins are a well-known multigene family of Ca 2+ -regulated phospholipid-binding and
membrane-binding proteins. Recent work employing annexin-knockdown or - knockout …
membrane-binding proteins. Recent work employing annexin-knockdown or - knockout …
Identity of p36K phosphorylated upon Rous sarcoma virus transformation with a protein purified from brush borders; calcium‐dependent binding to non‐erythroid …
V Gerke, K Weber - The EMBO journal, 1984 - embopress.org
Membrane vesicles derived from the apical side of procine intestinal epithelial cells retain,
after demembranation in the presence of calcium, two major proteins (I, II) which are released …
after demembranation in the presence of calcium, two major proteins (I, II) which are released …
Analysis of CD44-containing lipid rafts: recruitment of annexin II and stabilization by the actin cytoskeleton
S Oliferenko, K Paiha, T Harder, V Gerke… - The Journal of cell …, 1999 - rupress.org
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to
detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells…
detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells…
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes
…, A Strey, IS Thorey, R Reichelt, D Foell, V Gerke… - blood, 2004 - ashpublications.org
MRP14 (S100A9) is the major calcium-binding protein of neutrophils and monocytes.
Targeted gene disruption reveals an essential role of this S100 protein for transendothelial …
Targeted gene disruption reveals an essential role of this S100 protein for transendothelial …
[HTML][HTML] Annexins and membrane dynamics
V Gerke, SE Moss - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 1997 - Elsevier
Intracellular Ca2q signalling and Ca2q homeostasis are among the central problems in cell
biology that have received major attention for a number of decades. Fascinating and intricate …
biology that have received major attention for a number of decades. Fascinating and intricate …
[HTML][HTML] A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR
A Walther, K Riehemann, V Gerke - Molecular cell, 2000 - cell.com
The glucocorticoid-regulated protein annexin I (lipocortin I) has been shown to mediate
antiinflammatory activities of glucocorticoids, but the molecular basis of its action has remained …
antiinflammatory activities of glucocorticoids, but the molecular basis of its action has remained …