[HTML][HTML] Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis

V Prestigiacomo, A Weston, S Messner, F Lampart… - PloS one, 2017 - journals.plos.org
Background & Aims Currently most liver fibrosis research is performed in vivo, since suitable
alternative in vitro systems which are able to recapitulate the cellular events leading to liver …

[HTML][HTML] Nrf2 protects stellate cells from Smad-dependent cell activation

V Prestigiacomo, L Suter-Dick - PloS one, 2018 - journals.plos.org
<p>Hepatic stellate cells (HSC) orchestrate the deposition of extracellular matrix (ECM) and
are the primary effector of liver fibrosis. Several factors, including TGF-β1, PDGF and …

Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching

…, M Pirkl, M Hisano, V Prestigiacomo… - Life science …, 2022 - life-science-alliance.org
In melanoma, a switch from a proliferative melanocytic to an invasive mesenchymal phenotype
is based on dramatic transcriptional reprogramming which involves complex interactions …

[HTML][HTML] Rat multicellular 3D liver microtissues to explore TGF-β1 induced effects

V Prestigiacomo, A Weston, L Suter-Dick - Journal of pharmacological and …, 2020 - Elsevier
Chronic liver damage can lead to fibrosis, encompassing hepatocellular injury, activation of
Kupffer cells (KC), and activation of hepatic stellate cells (HSC). Inflammation and TGF-β1 …

[PDF][PDF] La cittą si sveglia fascista

V Prestigiacomo - Il volto di Palermo tra ventennio e dopoguerra, 2012 - nuovaipsa.com
L’idea di questo libro nasce il 22 giugno 2011. Quella notte sognavo di trovarmi a Donalegge,
un maniero madonita che probabilmente risale al 1085. Un luogo ricco di fascino che …

Investigation of the role of Nrf2 in hepatic stellate cells during liver fibrosis using in vitro models

V Prestigiacomo - 2018 - edoc.unibas.ch
Liver fibrosis is a reversible wound-healing response characterized by fibroblast proliferation
and extracellular matrix (ECM) remodelling. The development of fibrosis involves several …

[CITATION][C] The role of bile salts in cholestatic injury and fibrosis using a human 3D in vitro model

C Messner, L Mauch, S Mannino, V Prestigiacomo… - 2018 - irf.fhnw.ch

[CITATION][C] L'epoca pioneristica della Targa Florio

V Prestigiacomo - 2004 - Palermo, AAPIT

[CITATION][C] I Florio: regnanti senza corona

V Prestigiacomo - 2017 - Nuova Ipsa editore