User profiles for Vicki Plaks

Vicki Plaks

Postdoctoral fellow, University of California, San Francisco
Verified email at ucsf.edu
Cited by 11659

[HTML][HTML] Matrix metalloproteinases: regulators of the tumor microenvironment

K Kessenbrock, V Plaks, Z Werb - Cell, 2010 - cell.com
Extracellular proteolysis mediates tissue homeostasis. In cancer, altered proteolysis leads to
unregulated tumor growth, tissue remodeling, inflammation, tissue invasion, and metastasis…

[PDF][PDF] The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?

V Plaks, N Kong, Z Werb - Cell stem cell, 2015 - cell.com
Cancer stem cells (CSCs) are tumor cells that have the principal properties of self-renewal,
clonal tumor initiation capacity, and clonal long-term repopulation potential. CSCs reside in …

Axicabtagene ciloleucel in relapsed or refractory indolent non-Hodgkin lymphoma (ZUMA-5): a single-arm, multicentre, phase 2 trial

…, J Rosenblatt, JM Rossi, L Goyal, V Plaks… - The lancet …, 2022 - thelancet.com
Background Most patients with advanced-stage indolent non-Hodgkin lymphoma have multiple
relapses. We assessed axicabtagene ciloleucel autologous anti-CD19 chimeric antigen …

Circulating tumor cells

V Plaks, CD Koopman, Z Werb - Science, 2013 - science.org
The major cause of cancer-associated mortality is tumor metastasis, but our understanding
of this process is far from complete. During successful dissemination, tumor cells invade the …

[PDF][PDF] Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

ES Nakasone, HA Askautrud, T Kees, JH Park, V Plaks… - Cancer cell, 2012 - cell.com
Little is known about the dynamics of cancer cell death in response to therapy in the tumor
microenvironment. Intravital microscopy of chemotherapy-treated mouse mammary …

[HTML][HTML] Uterine DCs are crucial for decidua formation during embryo implantation in mice

V Plaks, T Birnberg, T Berkutzki, S Sela… - The Journal of …, 2008 - Am Soc Clin Investig
… In this issue of the JCI, Plaks et al. show, in a transgenic mouse model, that uDCs are
essential for pregnancy, as their … Vicki Plaks and Tal Birnberg contributed equally to this work. …

[HTML][HTML] Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma

…, Y Lin, A Ghobadi, JJ Kim, J Chou, V Plaks… - Nature medicine, 2022 - nature.com
Axicabtagene ciloleucel (axi-cel) is an anti-CD19 chimeric antigen receptor (CAR) T cell
therapy approved for relapsed/refractory large B cell lymphoma (LBCL) and has treatment with …

[PDF][PDF] Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis

V Plaks, A Brenot, DA Lawson, JR Linnemann… - Cell reports, 2013 - cell.com
Mammary epithelial stem cells are vital to tissue expansion and remodeling during various
phases of postnatal mammary development. Basal mammary epithelial cells are enriched in …

WST11, A Novel Water‐soluble Bacteriochlorophyll Derivative; Cellular Uptake, Pharmacokinetics, Biodistribution and Vascular‐targeted Photodynamic Activity Using …

O Mazor, A Brandis, V Plaks, E Neumark… - Photochemistry and …, 2005 - Wiley Online Library
WST11 is a novel negatively charged water‐soluble palladiumbacteriochlorophyll derivative
that was developed for vascular‐targeted photodynamic therapy (VTP) in our laboratory. …

MRI detection of transcriptional regulation of gene expression in transgenic mice

B Cohen, K Ziv, V Plaks, T Israely, V Kalchenko… - Nature medicine, 2007 - nature.com
Ferritin, the iron storage protein, was recently suggested to be a candidate reporter for the
detection of gene expression by magnetic resonance imaging (MRI). Here we report the …