The opposing roles of laminin-binding integrins in cancer
V Ramovs, L Te Molder, A Sonnenberg - Matrix Biology, 2017 - Elsevier
Integrins play an important role in cell adhesion by linking the cytoskeleton of cells to
components in the extracellular matrix. In this capacity, integrins cooperate with different cell …
components in the extracellular matrix. In this capacity, integrins cooperate with different cell …
[HTML][HTML] Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin
…, A Paulien Drenth, E van der Burg, V Ramovs… - Nature …, 2019 - nature.com
E-cadherin (CDH1) is a master regulator of epithelial cell adherence junctions and a well-established
tumor suppressor in Invasive Lobular Carcinoma (ILC). Intriguingly, somatic …
tumor suppressor in Invasive Lobular Carcinoma (ILC). Intriguingly, somatic …
[HTML][HTML] Integrin α3β1 is a key regulator of several protumorigenic pathways during skin carcinogenesis
V Ramovs, AK Garcia, M Kreft, A Sonnenberg - Journal of Investigative …, 2021 - Elsevier
Integrin α3β1 plays a crucial role in tumor formation in the two-stage chemical carcinogenesis
model (DMBA and TPA treatment). However, the mechanisms whereby the expression of …
model (DMBA and TPA treatment). However, the mechanisms whereby the expression of …
[HTML][HTML] Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo
V Ramovs, P Secades, JY Song, B Thijssen… - Breast Cancer …, 2019 - Springer
Background HER2-driven breast cancer is correlated with poor prognosis, especially during
its later stages. Numerous studies have shown the importance of the integrin α3β1 during …
its later stages. Numerous studies have shown the importance of the integrin α3β1 during …
[PDF][PDF] Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
Human induced pluripotent stem cell (hiPSC)-derived hair-bearing skin organoids offer exciting
new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited …
new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited …
[HTML][HTML] Generation and genetic repair of two human induced pluripotent cell lines from patients with Epidermolysis Bullosa simplex and dilated cardiomyopathy …
V Ramovs, I Fuentes, C Freund, H Mikkers… - Stem Cell Research, 2021 - Elsevier
Fibroblasts from two patients carrying a heterozygous mutation in the translation initiation
codon (c.2 T > G) of the kelch-like protein 24 (KLHL24) gene were used to generate human …
codon (c.2 T > G) of the kelch-like protein 24 (KLHL24) gene were used to generate human …
Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis
V Ramovs, AK Garcia, JY Song, I de Rink… - Life Science …, 2020 - life-science-alliance.org
Epidermal-specific deletion of integrin α3β1 almost completely prevents the formation of
papillomas during 7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate (…
papillomas during 7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate (…
Emergence and flight routes of the lesser horseshoe bats Rhinolophus hipposideros (Bechstein, 1800) from a church at Ljubljansko barje, central Slovenia
V Ramovš, S Zidar, M Zagmajster - Natura Sloveniae, 2010 - journals.uni-lj.si
The flight routes from roosts to feeding habitats are important for efficient conservation of
bats, but in Slovenia they are poorly known. Emergence and flight routes of the lesser …
bats, but in Slovenia they are poorly known. Emergence and flight routes of the lesser …
[PDF][PDF] Susana M. Chuva de Sousa Lopes, Christian Freund, Xavier Gidrol, 6 Christine L. Mummery, and Karine Raymond
Human induced pluripotent stem cell (hiPSC)-derived hair-bearing skin organoids offer exciting
new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited …
new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited …
[HTML][HTML] Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis
SV Novitskiy, E Forrester, MW Pickup, AE Gorska… - Breast Cancer …, 2014 - Springer
Introduction Transforming growth factor beta (TGFβ) plays a major role in the regulation of
tumor initiation, progression, and metastasis. It is depended on the type II TGFβ receptor (TβRII…
tumor initiation, progression, and metastasis. It is depended on the type II TGFβ receptor (TβRII…