User profiles for Valentin Heim

Valentin Johannes Heim

Walter and Eliza Hall Institute of Medical Research
Verified email at wehi.edu.au
Cited by 195

[HTML][HTML] NOD signaling and cell death

VJ Heim, CA Stafford, U Nachbur - Frontiers in cell and …, 2019 - frontiersin.org
Innate immune signaling and programmed cell death are intimately linked, and many
signaling pathways can regulate and induce both, transcription of inflammatory mediators or …

[PDF][PDF] IAPs regulate distinct innate immune pathways to co-ordinate the response to bacterial peptidoglycans

CA Stafford, KE Lawlor, VJ Heim, A Bankovacki… - Cell Reports, 2018 - cell.com
Inhibitors of apoptosis (IAPs) proteins are critical regulators of innate immune signaling
pathways and therefore have potential as drug targets. X-linked IAP (XIAP) and cellular IAP1 and …

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures

…, S Briese, C Arnold, I Kienes, V Heim… - Life Science …, 2019 - life-science-alliance.org
The receptor interacting serine/threonine kinase 2 (RIPK2) is essential for linking activation
of the pattern recognition receptors NOD1 and NOD2 to cellular signaling events. Recently, it …

A regulatory region on RIPK 2 is required for XIAP binding and NOD signaling activity

VJ Heim, LF Dagley, CA Stafford, FM Hansen… - EMBO …, 2020 - embopress.org
Signaling via the intracellular pathogen receptors nucleotide‐binding oligomerization
domain‐containing proteins NOD 1 and NOD 2 requires receptor interacting kinase 2 ( RIPK 2), an …

Genetic and environmental effects on the morphological asymmetry in the scale‐eating cichlid fish, Perissodus microlepis

HJ Lee, V Heim, A Meyer - Ecology and Evolution, 2015 - Wiley Online Library
The scale‐eating cichlid fish, Perissodus microlepis, from Lake Tanganyika are a well‐known
example of an asymmetry dimorphism because the mouth/head is either left‐bending or …

Genetic evidence for prevalence of alloparental care in a socially monogamous biparental cichlid fish, Perissodus microlepis, from Lake Tanganyika supports the “ …

HJ Lee, V Heim, A Meyer - Ecology and Evolution, 2016 - Wiley Online Library
Alloparental care – care for unrelated young – is rare in animals, and its ecological or
evolutionary advantages or, alternative maladaptive nature, remain unclear. We investigate …

ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin‐draining lymph nodes

…, H Anderton, S Zhang, A Kueh, V Heim… - … and Cell Biology, 2022 - Wiley Online Library
The role of RNA‐binding proteins of the CCCH‐containing family in regulating proinflammatory
cytokine production and inflammation is increasingly recognized. We have identified …

A regulatory interface on RIPK2 is required for XIAP binding and NOD signaling activity

VJ Heim, LF Dagley, CA Stafford, FM Hansen, E Clayer… - bioRxiv, 2020 - biorxiv.org
Signaling via the intracellular pathogen receptors Nucleotide-binding oligomerization
domain-containing proteins NOD1 and NOD2 requires Receptor Interacting Kinase 2 (RIPK2), an …

The role of C-reactive protein and white blood cell count in the prediction of length of stay in hospital and severity of odontogenic abscess

N Heim, V Wiedemeyer, RH Reich, M Martini - Journal of Cranio …, 2018 - Elsevier
Introduction Odontogenic infections and subsequent developing abscess remain to be a
potentially life-threatening event, due to septicemia, airway compression and spreading into …

[CITATION][C] A regulatory region onRIPK2 is required forXIAPbinding andNODsignaling activity

VJ Heim, LF Dagley, CA Stafford… - EMBO …, 2020 - … ST, HOBOKEN 07030-5774, NJ USA