[HTML][HTML] Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages
CKY Ng, E Dazert, T Boldanova, M Coto-Llerena… - Nature …, 2022 - nature.com
Proteogenomic analyses of hepatocellular carcinomas (HCC) have focused on early-stage,
HBV-associated HCCs. Here we present an integrated proteogenomic analysis of HCCs …
HBV-associated HCCs. Here we present an integrated proteogenomic analysis of HCCs …
Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis
…, J Cupovic, P Künzler, T Boldanova… - Life science …, 2020 - life-science-alliance.org
Infectious complications in patients with cirrhosis frequently initiate episodes of decompensation
and substantially contribute to the high mortality. Mechanisms of the underlying …
and substantially contribute to the high mortality. Mechanisms of the underlying …
Circulating cell-free DNA captures the intratumor heterogeneity in multinodular hepatocellular carcinoma
PURPOSE Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, with more
than 40% of patients initially diagnosed with multinodular HCCs. Although circulating cell-…
than 40% of patients initially diagnosed with multinodular HCCs. Although circulating cell-…
[HTML][HTML] Response prediction of hepatocellular carcinoma undergoing transcatheter arterial chemoembolization: unlocking the potential of CT texture analysis through …
Objectives To investigate if nested multiparametric decision tree models based on tumor
size and CT texture parameters from pre-therapeutic imaging can accurately predict …
size and CT texture parameters from pre-therapeutic imaging can accurately predict …
[HTML][HTML] Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model
Comprehensive molecular characterization of cancer subtypes is essential for predicting
clinical outcomes and searching for personalized treatments. We present bnClustOmics, a …
clinical outcomes and searching for personalized treatments. We present bnClustOmics, a …
[PDF][PDF] miR‐579‐3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3‐Kinase–Protein Kinase B Pathway in Chronically Inflamed …
…, S Uzun, S Piscuoglio, T Boldanova… - Hepatology …, 2022 - Wiley Online Library
Chronic liver inflammation causes continuous liver damage with progressive liver fibrosis and
cirrhosis, which may eventually lead to hepatocellular carcinoma (HCC). Whereas the 10‐…
cirrhosis, which may eventually lead to hepatocellular carcinoma (HCC). Whereas the 10‐…
[HTML][HTML] Computed tomography (CT) and magnetic resonance imaging (MRI) of diffuse liver disease: a multiparametric predictive modelling algorithm can aid …
…, C Zaugg, JE Gehweiler, T Boldanova… - … Imaging in Medicine …, 2022 - ncbi.nlm.nih.gov
Background Liver steatosis is common and tracking disease evolution to steatohepatitis and
cirrhosis is essential for risk stratification and resultant patient management. Consequently, …
cirrhosis is essential for risk stratification and resultant patient management. Consequently, …
[HTML][HTML] Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report
…, J Vosbeck, S Taha-Mehlitz, T Boldanova… - Communications …, 2022 - nature.com
Background Focal nodular hyperplasia (FNH) is typically considered a benign tumor of the
liver without malignant potential. The co-occurrence of FNH and hepatocellular carcinoma (…
liver without malignant potential. The co-occurrence of FNH and hepatocellular carcinoma (…
[PDF][PDF] Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization
T Boldanova, G Fucile, J Vosshenrich, A Suslov… - Cell Reports …, 2021 - cell.com
Although transarterial chemoembolization (TACE) is the most widely used treatment for
intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset …
intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset …
Proteogenomic characterization of hepatocellular carcinoma
CKY Ng, E Dazert, T Boldanova, M Coto-Llerena… - bioRxiv, 2021 - biorxiv.org
We performed a proteogenomic analysis of hepatocellular carcinomas (HCCs) across
clinical stages and etiologies. We identified pathways differentially regulated on the genomic, …
clinical stages and etiologies. We identified pathways differentially regulated on the genomic, …