The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

…, M Natsui, H Kosako, R Natsuyama, T Marutani… - Elife, 2020 - elifesciences.org
Most of peroxisomal matrix proteins including a hydrogen peroxide (H 2 O 2 )-decomposing
enzyme, catalase, are imported in a peroxisome-targeting signal type-1 (PTS1)-dependent …

Accumulation of type IV collagen in dilated ER leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP

T Marutani, A Yamamoto, N Nagai… - Journal of cell …, 2004 - journals.biologists.com
Hsp47 is an endoplasmic reticulum (ER)-resident molecular chaperone that is specific for
collagen. In Hsp47 –/– mouse embryos at 9.5 days postcoitus (dpc), immunostaining indicated …

Insufficient folding of type IV collagen and formation of abnormal basement membrane-like structure in embryoid bodies derived from Hsp47-null embryonic stem cells

…, H Kubota, E Adachi, N Nagai, T Marutani… - Molecular biology of …, 2004 - Am Soc Cell Biol
Hsp47 is a molecular chaperone that specifically recognizes procollagen in the endoplasmic
reticulum. Hsp47-null mouse embryos produce immature type I collagen and form …

Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum

…, K Nakayama, R Ohgi, T Marutani… - Life science …, 2018 - life-science-alliance.org
Peroxisome biogenesis disorders (PBDs) manifest as neurological deficits in the central
nervous system, including neuronal migration defects and abnormal cerebellum development. …

An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid β‐protein

T Maeda, T Marutani, K Zou, W Araki… - The FEBS …, 2009 - Wiley Online Library
The presenilin complex, consisting of presenilin, nicastrin, anterior pharynx defective‐1 and
presenilin enhancer‐2, constitutes γ‐secretase, which is required for the generation of …

ER-stress-inducible Herp, facilitates the degradation of immature nicastrin

T Marutani, T Maeda, C Tanabe, K Zou, W Araki… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Background Herp is an endoplasmic reticulum (ER)-stress-inducible membrane protein
harboring an ubiquitin-like domain (ULD). However, its biological functions are not fully …

Reconstitution of γ‐secretase by truncated presenilin (PS) fragments revealed that PS C‐terminal transmembrane domain is critical for formation of γ‐secretase …

H Shiraishi, T Marutani, HQ Wang, Y Maeda… - Genes to …, 2006 - Wiley Online Library
The presenilin (PS) complex, including PS, nicastrin (NCT), APH‐1 and PEN‐2, is essential
for γ‐secretase activity. Previously, the PS C‐terminal tail was shown to be essential for γ‐…

The effect of site quality on economically optimal stand management

T Marutani - Journal of forest economics, 2010 - Elsevier
This paper proposes a discrete-time type timber harvesting model for simultaneously
determining (i) the optimal quantity of seedlings to be planted, (ii) the optimal quantities of timber …

Halal in Japan: History, issues and problems-the effect of the" Halal Boom" phenomenon on Japanese society and industry

YA Adidaya - 2016 - duo.uio.no
The development of Halal has recently spread in Japan and become a new trending topic in
Muslim tourism and Japanese businesses. But Halal in Japan is not that new. It is said that …

[HTML][HTML] A case of recurrent hemorrhages due to a chronic expanding encapsulated intracranial hematoma

A Marutani, K Nagata, J Deguchi, Y Nikaido… - Case Reports in …, 2015 - karger.com
Few case reports of encapsulated intracranial hematoma (EIH) exist, and the mechanisms
underlying the onset and enlargement of EIH remain unclear. Here, we report on a 39-year-…