Obesity is becoming a global epidemic in both children and adults. It is associated with
numerous comorbidities such as cardiovascular diseases (CVD), type 2 diabetes, hypertension, …

Resistant hypertension is a common clinical problem faced by both primary care clinicians
and specialists. While the exact prevalence of resistant hypertension is unknown, clinical …

Allelic deletions involving chromosome 18q occur in more than 70 percent of colorectal
cancers. Such deletions are thought to signal the existence of a tumor suppressor gene in the …

… Perros P, Colley S, Boelaert K, Evans C, Evans RM, Gerrard GE, Gilbert JA, Harrison B,
Johnson SJ, Giles TE, Moss L, Lewington V, Newbold KL, Taylor J, Thakker RV, Watkinson J …

Finally! A handbook arising from the last 15 years of neuroscience, clinical trials and clinical
reasoning science is here for both clinicians and pain sufferers. Graded Motor Imagery (GMI…

R-loops are nucleic acid structures formed by an RNA:DNA hybrid and unpaired single-stranded
DNA that represent a source of genomic instability in mammalian cells 1 , 2 , 3 – 4 . …

Patent foramen ovale (PFO) is implicated in platypnea-orthodeoxia, stroke and decompression
sickness (DCS) in divers and astronauts. However, PFO size in relation to clinical illness …

… DeMaria, Robert DiBianco, Thomas J. Donohue, Paul Douglass, W. Bruce Dunkman, Uri
Elkayam, Rodney H. … Giles, Michael M. Givertz, Steven Goldman, Steven R. Goldsmith, Sidney …

Bidirectional (anterograde and retrograde) motor-based intraflagellar transport (IFT) governs
cargo transport and delivery processes that are essential for primary cilia growth and …

Since the publication of a paper by the American Society of Hypertension, Inc. Writing Group
in 2003, some refinements have occurred in the definition of hypertension. Blood pressure …