The postsynaptic density

TM Böckers - Cell and tissue research, 2006 - Springer
Glutamatergic synapses in the central nervous system are characterized by an electron-dense
web underneath the postsynaptic membrane; this web is called the postsynaptic density (…

[HTML][HTML] Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

…, R Mantegazza, V Broccoli, TM Böckers… - Journal of Biological …, 2011 - ASBMB
Shank3/PROSAP2 gene mutations are associated with cognitive impairment ranging from
mental retardation to autism. Shank3 is a large scaffold postsynaptic density protein …

Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory

…, U Rauch, H Matthies, H Meyer, M Krug… - … and cellular biology, 2002 - Taylor & Francis
Brevican is a brain-specific proteoglycan which is found in specialized extracellular matrix
structures called perineuronal nets. Brevican increases the invasiveness of glioma cells in …

The gross anatomy course: an analysis of its importance

A Böckers, L Jerg‐Bretzke, C Lamp… - Anatomical sciences …, 2010 - Wiley Online Library
The gross anatomy dissection course is a cost‐intensive piece of undergraduate medical
education that students and professionals alike describe as very important within the overall …

[HTML][HTML] Synaptic scaffolding proteins in rat brain: ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein α-fodrin

TM Böckers, MG Mameza, MR Kreutz… - Journal of Biological …, 2001 - ASBMB
The postsynaptic density is the ultrastructural entity containing the neurotransmitter reception
apparatus of excitatory synapses in the brain. A recently identified family of multidomain …

Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of …

TM Böckers, M Segger-Junius, P Iglauer… - Molecular and Cellular …, 2004 - Elsevier
Shank proteins are scaffolding proteins in the postsynaptic density of excitatory synapses in
the mammalian brain. In situ hybridization revealed that Shank1/SSTRIP and Shank2/…

[HTML][HTML] Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes

…, K Achberger, AC Ludolph, S Liebau, TM Böckers - Stem cell …, 2015 - Elsevier
Striated skeletal muscle cells from humans represent a valuable source for in vitro studies of
the motoric system as well as for pathophysiological investigations in the clinical settings. …

Apoptotic versus necrotic characteristics of retinal ganglion cell death after partial optic nerve injury

A BIEN, CI SEIDENBECHER, TM BÖCKERS… - Journal of …, 1999 - liebertpub.com
We have investigated time course and characteristics of retinal ganglion cell (RGC) death
after partial optic nerve injury. In situ end labeling of DNA fragments with the terminal …

[HTML][HTML] Identification and functional characterization of rare SHANK2 variants in schizophrenia

…, G Schratt, MM Nöthen, TM Böckers, M Rietschel… - Molecular …, 2015 - nature.com
Recent genetic data on schizophrenia (SCZ) have suggested that proteins of the postsynaptic
density of excitatory synapses have a role in its etiology. Mutations in the three SHANK …

The use of a mobile learning tool by medical students in undergraduate anatomy and its effects on assessment outcomes

…, DAC Messerer, TM Böckers, A Böckers - Anatomical sciences …, 2020 - Wiley Online Library
Hand‐held devices have revolutionized communication and education in the last decade.
Consequently, mobile learning (m‐learning) has become popular among medical students. …