User profiles for Thomas D Pollard

Thomas D Pollard

- Verified email at yale.edu - Cited by 79436

Thomas D Pollard

- Verified email at ucl.ac.uk - Cited by 444

[HTML][HTML] Cellular motility driven by assembly and disassembly of actin filaments

TD Pollard, GG Borisy - Cell, 2003 - cell.com
Motile cells extend a leading edge by assembling a branched network of actin filaments that
produces physical force as the polymers grow beneath the plasma membrane. A core set of …

Additive manufacturable materials for electrochemical biosensor electrodes

M Elbadawi, JJ Ong, TD Pollard… - Advanced Functional …, 2021 - Wiley Online Library
With the impending Industrial Revolution 4.0, the information produced by sensors will be
central in many applications. This includes the healthcare sector, where affordable healthcare …

Regulation of actin filament assembly by Arp2/3 complex and formins

TD Pollard - Annu. Rev. Biophys. Biomol. Struct., 2007 - annualreviews.org
This review summarizes what is known about the biochemical and biophysical mechanisms
that initiate the assembly of actin filaments in cells. Assembly and disassembly of these …

Actin, a central player in cell shape and movement

TD Pollard, JA Cooper - science, 2009 - science.org
The protein actin forms filaments that provide cells with mechanical support and driving forces
for movement. Actin contributes to biological processes such as sensing environmental …

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

…, JA Heuser, TD Pollard - Proceedings of the …, 1998 - National Acad Sciences
The Arp2/3 complex is a stable assembly of seven protein subunits including two actin-related
proteins (Arp2 and Arp3) and five novel proteins. Previous work showed that this complex …

Molecular mechanisms controlling actin filament dynamics in nonmuscle cells

TD Pollard, L Blanchoin… - Annual review of …, 2000 - annualreviews.org
▪ Abstract We review how motile cells regulate actin filament assembly at their leading edge.
Activation of cell surface receptors generates signals (including activated Rho family …

Actin and actin-binding proteins. A critical evaluation of mechanisms and functions

TD Pollard, JA Cooper - Annual review of biochemistry, 1986 - annualreviews.org
At present there is a rather complete picture of how the primary structure of actin varies
throughout the phylogenetic tree and the detailed three-dimensional structure of actin is nearly …

Rate constants for the reactions of ATP-and ADP-actin with the ends of actin filaments.

TD Pollard - The Journal of cell biology, 1986 - rupress.org
I measured the rate of elongation at the barbed and pointed ends of actin filaments by electron
microscopy with Limulus sperm acrosomal processes as nuclei. With improvements in the …

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

…, RC May, ME Hall, TD Pollard - Proceedings of the …, 1999 - National Acad Sciences
The Arp2/3 complex, a stable assembly of two actin-related proteins (Arp2 and Arp3) with five
other subunits, caps the pointed end of actin filaments and nucleates actin polymerization …

[BOOK][B] Cell Biology E-Book: Cell Biology E-Book

TD Pollard, WC Earnshaw, J Lippincott-Schwartz… - 2022 - books.google.com
Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation
for students entering research or health care career paths. Award winning illustrations help …