Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil
…, VH Nascimento, MA Suchard, TA Bowden… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
[PDF][PDF] Antibody evasion by the P. 1 strain of SARS-CoV-2
…, MA Williams, DR Hall, RJG Hulswit, TA Bowden… - Cell, 2021 - cell.com
Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. …
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. …
[PDF][PDF] Case study: prolonged infectious SARS-CoV-2 shedding from an asymptomatic immunocompromised individual with cancer
Long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding was
observed from the upper respiratory tract of a female immunocompromised individual with …
observed from the upper respiratory tract of a female immunocompromised individual with …
Zika virus in the Americas: early epidemiological and genetic findings
Brazil has experienced an unprecedented epidemic of Zika virus (ZIKV), with ~30,000 cases
reported to date. ZIKV was first detected in Brazil in May 2015, and cases of microcephaly …
reported to date. ZIKV was first detected in Brazil in May 2015, and cases of microcephaly …
[HTML][HTML] Exploitation of glycosylation in enveloped virus pathobiology
Y Watanabe, TA Bowden, IA Wilson… - Biochimica et Biophysica …, 2019 - Elsevier
Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to glycosylate …
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to glycosylate …
[HTML][HTML] Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
…, OG Pybus, JS McLellan, IA Wilson, TA Bowden… - Nature …, 2020 - nature.com
Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential. …
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential. …
Toremifene interacts with and destabilizes the Ebola virus glycoprotein
Ebola viruses (EBOVs) are responsible for repeated outbreaks of fatal infections, including
the recent deadly epidemic in West Africa. There are currently no approved therapeutic drugs …
the recent deadly epidemic in West Africa. There are currently no approved therapeutic drugs …
Identification of common deletions in the spike protein of severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus first
identified in December 2019. Notable features that make SARS-CoV-2 distinct from most …
identified in December 2019. Notable features that make SARS-CoV-2 distinct from most …
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2
TA Bowden, AR Aricescu, RJC Gilbert… - Nature structural & …, 2008 - nature.com
Nipah and Hendra viruses are emergent paramyxoviruses, causing disease characterized
by rapid onset and high mortality rates, resulting in their classification as Biosafety Level 4 …
by rapid onset and high mortality rates, resulting in their classification as Biosafety Level 4 …
[HTML][HTML] Evidence for henipavirus spillover into human populations in Africa
…, TE Yun, A Park, TT Zachariah, TA Bowden… - Nature …, 2014 - nature.com
Zoonotic transmission of lethal henipaviruses (HNVs) from their natural fruit bat reservoirs to
humans has only been reported in Australia and South/Southeast Asia. However, a recent …
humans has only been reported in Australia and South/Southeast Asia. However, a recent …