Objective— Cord blood–derived human endothelial colony-forming cells (ECFCs) bear a
high proliferative capacity and potently enhance tissue neovascularization in vivo. Here, we …

Objective—Vasculogenic progenitor cell therapy for ischemic diseases bears great potential
but still requires further optimization for justifying its clinical application. Here, we …

Meiosis is initiated by a double-strand break (DSB) introduced in the DNA by a highly controlled
process that is repaired by recombination. In many organisms, recombination occurs at …

OBJECTIVE It has been shown that vascular progenitors from patients with diabetes are
dysfunctional. However, therapeutic strategies to counteract their reduced functional capacity …

PR domain containing protein 9 (PRDM9) is a meiosis-specific, multi-domain protein that
regulates the location of recombination hotspots by targeting its DNA recognition sequence for …

Background In compliance with national and international guidelines, non-pregnant women
with cervical intraepithelial neoplasia grade 3 should be treated by cervical conization. …

Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal
neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, …

The transmembrane ABC transporters P‐glycoprotein (P‐gp) and breast cancer resistance
protein (BCRP) are widely recognized for their role in cancer multidrug resistance and …

PRDM9 is a trans-acting factor directing meiotic recombination to specific DNA-binding sites
by its zinc finger (ZnF) array. It was suggested that PRDM9 is a multimer; however, we do …

Sarcopenia is frequent in liver cirrhosis (LC) where it is associated with morbidity and mortality.
However, prognostic scores such as model for end-stage liver disease (MELD), MELD-…