Molecular profiles of tumors and tumor-associated cells hold great promise as biomarkers of
clinical outcomes. However, existing data sets are fragmented and difficult to analyze …

Background We used modeling techniques to assess the relative and absolute
contributions of screening mammography and adjuvant treatment to the reduction in breast-cancer …

Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis.
We used single-cell “mass cytometry” to examine healthy human bone marrow, measuring …

The ability to analyze multiple single-cell parameters is critical for understanding cellular
heterogeneity. Despite recent advances in measurement technology, methods for analyzing …

Follicular lymphoma (FL) is incurable with conventional therapies and has a clinical course
typified by multiple relapses after therapy. These tumors are genetically characterized by B-…

Advances in multiplexed in situ imaging are revealing important insights in spatial biology.
However, cell type identification remains a major challenge in imaging analysis, with most …

Purpose To identify prognostic imaging biomarkers in non–small cell lung cancer (NSCLC)
by means of a radiogenomics strategy that integrates gene expression and medical images …

The application of primary organoid cultures containing epithelial and mesenchymal elements
to cancer modeling holds promise for combining the accurate multilineage differentiation …

… Plevritis, principal investigator). Drs. Mandelblatt and Cronin were the writing and
coordinating committee for the project; all other collaborators are listed in alphabetical order. …

Approximately 60% of patients with large B cell lymphoma treated with chimeric antigen
receptor (CAR) T cell therapies targeting CD19 experience disease progression, and …