[PDF][PDF] Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells
Cancer cells without mitochondrial DNA (mtDNA) do not form tumors unless they reconstitute
oxidative phosphorylation (OXPHOS) by mitochondria acquired from host stroma. To …
oxidative phosphorylation (OXPHOS) by mitochondria acquired from host stroma. To …
Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion
SW Kim, Y Jin, JH Shin, ID Kim, HK Lee, S Park… - Neurobiology of …, 2012 - Elsevier
High mobility group box 1 (HMGB1) is an endogenous danger signal molecule. In a
previous report, we showed that HMGB1 is massively released during NMDA-induced acute …
previous report, we showed that HMGB1 is massively released during NMDA-induced acute …
[HTML][HTML] Diagnosis of bladder cancer and prediction of survival by urinary metabolomics
Bladder cancer (BC) is a common cancer but diagnostic modalities, such as cystoscopy and
urinary cytology, have limitations. Here, high-performance liquid chromatography-…
urinary cytology, have limitations. Here, high-performance liquid chromatography-…
[HTML][HTML] Urine-NMR metabolomics for screening of advanced colorectal adenoma and early stage colorectal cancer
Although colorectal cancer (CRC) is considered one of the most preventable cancers, no
non-invasive, accurate diagnostic tool to screen CRC exists. We explored the potential of urine …
non-invasive, accurate diagnostic tool to screen CRC exists. We explored the potential of urine …
A new NMR-based metabolomics approach for the diagnosis of biliary tract cancer
H Wen, SS Yoo, J Kang, HG Kim, JS Park, S Jeong… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Biliary tract cancer is highly lethal at presentation, with increasing
mortality worldwide. Current diagnostic measures employing multiple criteria such as imaging…
mortality worldwide. Current diagnostic measures employing multiple criteria such as imaging…
NMR-based metabolomics approach for the differentiation of ginseng (Panax ginseng) roots from different origins
…, S Kang, HN Kwon, JH Park, SW Kwon, S Park - Archives of pharmacal …, 2008 - Springer
Agro-herbal materials vary in prices and qualities depending on the origin and age and the
differentiation is both scientific and public health issue. Here, we describe a metabolomics …
differentiation is both scientific and public health issue. Here, we describe a metabolomics …
Application of a 1H Nuclear Magnetic Resonance (NMR) Metabolomics Approach Combined with Orthogonal Projections to Latent Structure-Discriminant Analysis as …
Correct identification of the origins of herbal medical products is becoming increasingly
important in tandem with the growing interest in alternative medicine. However, visual inspection …
important in tandem with the growing interest in alternative medicine. However, visual inspection …
[HTML][HTML] Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress
…, N Kim, YS Yuk, SY Cha, Y Lee, JK Ryu, S Park… - Nature …, 2017 - nature.com
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate
pathway (PPP) during epithelial–mesenchymal transition (EMT) is not well-understood. Here …
pathway (PPP) during epithelial–mesenchymal transition (EMT) is not well-understood. Here …
[PDF][PDF] Psat1-dependent fluctuations in α-ketoglutarate affect the timing of ESC differentiation
…, JH Kim, YA Kim, YK Jeon, DH Chung, X Jin, S Park… - Cell metabolism, 2016 - cell.com
Embryonic stem cells (ESCs) undergo coordinated epigenetic and metabolic changes to
differentiate properly. However, the precise mechanisms by which these alterations are fine-…
differentiate properly. However, the precise mechanisms by which these alterations are fine-…
A serum marker for early pancreatic cancer with a possible link to diabetes
…, SS Hong, KH Jung, S Kang, MS Park… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Pancreatic cancer (PC) has a grim prognosis, and an early diagnostic biomarker
has been highly desired. The molecular link between diabetes and PC has not been well …
has been highly desired. The molecular link between diabetes and PC has not been well …