Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

Extracellular vesicles (EVs) have been shown to transfer various molecules, including functional
RNA between cells and this process has been suggested to be particularly relevant in …

The intestinal microbiota influences mammalian host physiology in health and disease
locally in the gut but also in organs devoid of direct contact with bacteria such as the liver and …

Mechanisms behind how the immune system signals to the brain in response to systemic
inflammation are not fully understood. Transgenic mice expressing Cre recombinase …

Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

New neurons are continuously added in specific regions of the adult mammalian central
nervous system. These neurons are derived from multipotent stem cells whose identity has …

New neurons are generated from stem cells in a few regions of the adult mammalian brain.
Here we provide evidence for the generation of dopaminergic projection neurons of the type …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids…

The adult human brain retains the capacity to generate new neurons in the hippocampal
formation ( Eriksson et al., 1998 ) and neuronal progenitor cells (NPCs) in the forebrain ( …

Extracellular RNA (exRNA) has emerged as an important transducer of intercellular communication.
Advancing exRNA research promises to revolutionize biology and transform clinical …