To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource (https://…

Individualized medicine is the healthcare strategy that rebukes the idiomatic dogma of ‘losing
sight of the forest for the trees’. We are entering a new era of healthcare where it is no …

Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Porous silicon (pSi) is emerging as a promising material in the development of nanovectors
for the systemic delivery of therapeutic and imaging agents. The integration of …

In this study, we investigate a novel in vitro model to mimic heterogeneous breast tumors
without the use of a scaffold while allowing for cell-cell and tumor-fibroblast interactions. …

The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

RNA-seq is increasingly used for quantitative profiling of small RNAs (for example, microRNAs,
piRNAs and snoRNAs) in diverse sample types, including isolated cells, tissues and cell-…

Glioblastoma (GBM) is characterized by aberrant vascularization and a complex tumor
microenvironment. The failure of anti-angiogenic therapies suggests pathways of GBM …

Given the increasing interest in their use as disease biomarkers, the establishment of
reproducible, accurate, sensitive, and specific platforms for microRNA (miRNA) quantification in …

As the cost of next-generation sequencing has decreased, library preparation costs have
become a more significant proportion of the total cost, especially for high-throughput …