User profiles for Sridharan Ganesan
 | Sridharan GanesanSenior Microbiologist at FIND Verified email at finddx.org Cited by 115 |
Dynamic regulation of NK cell responsiveness
Natural killer (NK) cells deliver cytotoxic granules and immunomodulatory cytokines in
response to transformed and virally infected cells. NK cell functions are under the control of a …
response to transformed and virally infected cells. NK cell functions are under the control of a …
Carcinoma-associated fibroblast–like differentiation of human mesenchymal stem cells
Carcinoma-associated fibroblasts (CAF) have recently been implicated in important aspects
of epithelial solid tumor biology, such as neoplastic progression, tumor growth, angiogenesis…
of epithelial solid tumor biology, such as neoplastic progression, tumor growth, angiogenesis…
[HTML][HTML] Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells
During infection and inflammation, dendritic cells (DC) provide priming signals for natural
killer (NK) cells via mechanisms distinct from their antigen processing and presentation …
killer (NK) cells via mechanisms distinct from their antigen processing and presentation …
Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch
IL-15 priming of NK cells is a broadly accepted concept, but the dynamics and underlying
molecular mechanisms remain poorly understood. We show that as little as 5 min of IL-15 …
molecular mechanisms remain poorly understood. We show that as little as 5 min of IL-15 …
[HTML][HTML] Inhibitory receptor crosslinking quantitatively dampens calcium flux induced by activating receptor triggering in NK cells
Natural killer (NK) cell function is regulated by a balance between activating and inhibitory
receptors, but the details of this receptor interplay are not extensively understood. We …
receptors, but the details of this receptor interplay are not extensively understood. We …
MHC class I molecules co‐stimulate NK1.1 signaling and enhance Ca2+ flux in murine NK cells.
Keywords: calcium flux; cross-linking; Ly49 receptors; MHC class I; NK cell EN calcium flux
cross-linking Ly49 receptors MHC class I NK cell 2531 2534 4 10/07/21 20211001 NES …
cross-linking Ly49 receptors MHC class I NK cell 2531 2534 4 10/07/21 20211001 NES …
A brief IL-15 pulse results in JAK3-dependent phosphorylation of ITAM-associated signaling molecules and a long-lasting priming imprint in mouse NK cells
TT Luu, NA Nguyen, S Ganesan, S Meinke… - Available at SSRN …, 2019 - papers.ssrn.com
Interleukin-15 (IL-15) is responsible for natural killer (NK) cell priming but the dynamics, kinetics
and molecular mechanisms of NK cell priming are not well characterised. We here show …
and molecular mechanisms of NK cell priming are not well characterised. We here show …
Full-scale evaluation of THMs formation and minimization of THMs via chloramination
UG Erdal, K Chaney, S Ganesan, GT Daigger - WEFTEC 2008, 2008 - accesswater.org
Chlorine has been and is still widely used chemical to disinfect wastewater. Trihalomethanes
(THMs) and other disinfection byproducts (DBPs) are formed when chlorine reacts with …
(THMs) and other disinfection byproducts (DBPs) are formed when chlorine reacts with …
Grey wolf optimisation‐based feature selection and classification for facial emotion recognition
NP Nirmala Sreedharan, B Ganesan… - IET …, 2018 - Wiley Online Library
The channels used to convey the human emotions consider actions, behaviours, poses,
facial expressions, and speech. An immense research has been carried out to analyse the …
facial expressions, and speech. An immense research has been carried out to analyse the …
Include: A large scale dataset for indian sign language recognition
Indian Sign Language (ISL) is a complete language with its own grammar, syntax, vocabulary
and several unique linguistic attributes. It is used by over 5 million deaf people in India. …
and several unique linguistic attributes. It is used by over 5 million deaf people in India. …