Background: Lactobacillus casei is a nonpathogenic gram-positive bacterium widely used
in dairy products and has been shown to enhance the cellular immunity of the host. Methods: …

The common marmoset (Callithrix jacchus) is increasingly attractive for use as a non-human
primate animal model in biomedical research. It has a relatively high reproduction rate for a …

The role of T helper type 1 (Th1) and Th2 cells in tumor immunity was investigated using Th
cells induced from ovalbumin (OVA)-specific T cell receptor transgenic mice. Although Th1 …

804 HONJO & HABU most of which differentiate from stem cells in the bone marrow. Among
these only Band T lymphocytes are responsible for antigen recognition. B cells, recognizing …

The thymic microenvironment is required for T cell development in vivo. However, in vitro
studies have shown that when hematopoietic progenitors acquire Notch signaling via Delta-like …

Notch receptors and their ligands contribute to many developmental systems, but it is not
apparent how they function after birth, as their null mutants develop severe defects during …

Potent immunosuppressive drugs have significantly improved early patient survival after liver
transplantation (LT). However, long‐term results remain unsatisfactory because of adverse …

We have demonstrated that intestinal epithelial cells produce interleukin 7 (IL-7), and IL-7
serves as a potent regulatory factor for proliferation of intestinal mucosal lymphocytes …

Mounting evidence suggests that natural killer cells (NK) play an important part in the destruction
of incipient tumours. If that is so, the destruction of NK cells in vivo should allow tumour …

CD100 belongs to the semaphorin family, several members of which are known to act as
repulsive axonal guidance factors during neuronal development. We have previously …