User profiles for Shoeb Ikhlas

Shoeb Ikhlas

Albert Einstein College of Medicine, New York, USA
Verified email at einsteinmed.org
Cited by 283

Occurrence, toxicity and endocrine disrupting potential of Bisphenol-B and Bisphenol-F: A mini-review

A Usman, S Ikhlas, M Ahmad - Toxicology Letters, 2019 - Elsevier
Recent imposition of restriction on the use of Bisphenol-A (BPA) paved the way for entry of
its analogues in the market. Bisphenol-B and Bisphenol-F are the major analogues of …

Metformin: Insights into its anticancer potential with special reference to AMPK dependent and independent pathways

S Ikhlas, M Ahmad - Life sciences, 2017 - Elsevier
Metformin has been known for its antidiabetic effects for decades and is used as a first line
therapy in type 2 diabetes. But recently its anticancer potential has also been discovered. …

Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system

S Ikhlas, A Usman, D Kim, D Cai - Life Science Alliance, 2022 - life-science-alliance.org
Murine neural stem cells (NSCs) were recently shown to release piRNA-containing
exosomes/microvesicles (Ex/Mv) for exerting antiviral immunity, but it remains unknown if these Ex/…

[PDF][PDF] Innate and adaptive immunity of murine neural stem cell-derived piRNA exosomes/microvesicles against pseudotyped SARS-CoV-2 and HIV-based lentivirus

B Yu, S Ikhlas, C Ruan, X Zhong, D Cai - IScience, 2020 - cell.com
By testing pseudotyped SARS-CoV-2 and HIV-based lentivirus, this study reports that
exosomes/microvesicles (Ex/Mv) isolated from murine hypothalamic neural stem/progenitor cells (…

In vitro study to evaluate the cytotoxicity of BPA analogues based on their oxidative and genotoxic potential using human peripheral blood cells

S Ikhlas, A Usman, M Ahmad - Toxicology in vitro, 2019 - Elsevier
Although Bisphenol-A (BPA) has been found to exhibit toxicological properties such as
genotoxicity and oxidative stress, yet there is very little data available on its analogues. Since the …

Binding studies of guggulsterone-E to calf thymus DNA by multi-spectroscopic, calorimetric and molecular docking studies

S Ikhlas, M Ahmad - Spectrochimica Acta Part A: Molecular and …, 2018 - Elsevier
Guggulsterone, a sterol found in plants is used as an ayurvedic medicine for many diseases
such as obesity, internal tumors, ulcers etc. E and Z are two isoforms of guggulsterone, …

Comparative study of the interactions between bisphenol-A and its endocrine disrupting analogues with bovine serum albumin using multi-spectroscopic and …

S Ikhlas, A Usman, M Ahmad - Journal of Biomolecular Structure …, 2019 - Taylor & Francis
Full article: Comparative study of the interactions between bisphenol-A and its endocrine
disrupting analogues with bovine serum albumin using multi-spectroscopic and molecular …

Acute and sub-acute bisphenol-B exposures adversely affect sperm count and quality in adolescent male mice

S Ikhlas, M Ahmad - Chemosphere, 2020 - Elsevier
Bisphenol-B (BPB), an analogue of bisphenol-A is used in the plastic industry. It has been
found to leach from plastic containers leading to its contamination in canned food products. …

Genotoxicity and Mutagenicity of Bisphenol A

S Ikhlas, A Usman - 2022 - books.rsc.org
Bisphenol A (BPA) is a well-known endocrine-disrupting chemical. Various factors, including
extensive environmental contamination, ubiquitous human exposure, and low-dose effects, …

[PDF][PDF] TOXICITY ASSESSMENT OF BISPHENOL-B, A POTENTIAL ENDOCRINE DISRUPTING CHEMICAL

S IKHLAS - 2019 - eprints.csirexplorations.com
In the first chapter an attempt was made to study the endocrine disrupting potential of BPB
using in silico techniques. A webserver (endocrine disruptome) capable of performing …