User profiles for Satoru Torii
Satoru ToriiTMDU Verified email at tmd.ac.jp Cited by 13400 |
Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway
H Hanafusa, S Torii, T Yasunaga, E Nishida - Nature cell biology, 2002 - nature.com
Sprouty (Spry) inhibits signalling by receptor tyrosine kinases; however, the molecular
mechanism underlying this function has not been defined. Here we show that after stimulation by …
mechanism underlying this function has not been defined. Here we show that after stimulation by …
[HTML][HTML] Sef is a spatial regulator for Ras/MAP kinase signaling
S Torii, M Kusakabe, T Yamamoto, M Maekawa… - Developmental cell, 2004 - cell.com
Spatiotemporal control of the Ras/ERK MAP kinase signaling pathway is among the key
mechanisms for regulating a wide variety of cellular processes. In this study, we report that …
mechanisms for regulating a wide variety of cellular processes. In this study, we report that …
ERK MAP kinase in G1 cell cycle progression and cancer
S Torii, T Yamamoto, Y Tsuchiya, E Nishida - Cancer science, 2006 - Wiley Online Library
The extracellular‐signal‐regulated kinase (ERK) mitogen‐activated protein (MAP) kinase
signaling pathway plays an important role in various cellular responses, including cell …
signaling pathway plays an important role in various cellular responses, including cell …
[HTML][HTML] Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the …
H Hanafusa, S Torii, T Yasunaga, K Matsumoto… - Journal of Biological …, 2004 - ASBMB
Src homology 2-containing phosphotyrosine phosphatase (Shp2) functions as a positive
effector in receptor tyrosine kinase (RTK) signaling immediately proximal to activated receptors. …
effector in receptor tyrosine kinase (RTK) signaling immediately proximal to activated receptors. …
Regulatory mechanisms and function of ERK MAP kinases
S Torii, K Nakayama, T Yamamoto… - Journal of …, 2004 - academic.oup.com
Spatiotemporal control of the Ras/ERK MAP kinase signaling pathway is a key factor for
determining the specificity of cellular responses including cell proliferation, cell differentiation …
determining the specificity of cellular responses including cell proliferation, cell differentiation …
Live cell imaging of mitochondrial autophagy with a novel fluorescent small molecule
H Iwashita, S Torii, N Nagahora, M Ishiyama… - ACS chemical …, 2017 - ACS Publications
There has been a growing interest in mitophagy, mitochondria-selective autophagy, which
plays an essential role in maintaining intracellular homeostasis. We have developed a small-…
plays an essential role in maintaining intracellular homeostasis. We have developed a small-…
Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress‐induced autophagy
Autophagy is an evolutionary conserved process that degrades subcellular constituents.
Unlike starvation‐induced autophagy, the molecular mechanism of genotoxic stress‐induced …
Unlike starvation‐induced autophagy, the molecular mechanism of genotoxic stress‐induced …
[HTML][HTML] Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming
Direct cardiac reprogramming from fibroblasts can be a promising approach for disease
modeling, drug screening, and cardiac regeneration in pediatric and adult patients. However, …
modeling, drug screening, and cardiac regeneration in pediatric and adult patients. However, …
[HTML][HTML] Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy
Alternative autophagy is an autophagy-related protein 5 (Atg5)-independent type of
macroautophagy. Unc51-like kinase 1 (Ulk1) is an essential initiator not only for Atg5-dependent …
macroautophagy. Unc51-like kinase 1 (Ulk1) is an essential initiator not only for Atg5-dependent …
[HTML][HTML] Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration
Alternative autophagy is an Atg5/Atg7-independent type of autophagy that contributes to
various physiological events. We here identify Wipi3 as a molecule essential for alternative …
various physiological events. We here identify Wipi3 as a molecule essential for alternative …