Elevated serum soluble vascular endothelial growth factor receptor 1 (sVEGFR-1) levels in women with preeclampsia

…, Y Hirota, X Ruimeng, T Hirata, S Takeda… - The Journal of …, 2003 - academic.oup.com
Hoping to get more insight into a role of vascular endothelial growth factor (VEGF), a putative
substance involved in the development of preeclampsia, we measured concentrations of …

Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium

…, L Woods, R Lucciola, Y Hou Lee, S Takeda… - elife, 2017 - elifesciences.org
10.7554/eLife.31274.001 In cycling human endometrium, menstruation is followed by rapid
estrogen-dependent growth. Upon ovulation, progesterone and rising cellular cAMP levels …

Loss of endometrial plasticity in recurrent pregnancy loss

…, JD Moore, G Patel, JKY Chan, S Takeda… - Stem …, 2016 - academic.oup.com
Menstruation drives cyclic activation of endometrial progenitor cells, tissue regeneration, and
maturation of stromal cells, which differentiate into specialized decidual cells prior to and …

[PDF][PDF] Structure of the miniature type VF CRISPR-Cas effector enzyme

SN Takeda, R Nakagawa, S Okazaki, H Hirano… - Molecular Cell, 2021 - cell.com
RNA-guided DNA endonucleases derived from CRISPR-Cas adaptive immune systems are
widely used as powerful genome-engineering tools. Among the diverse CRISPR-Cas …

[HTML][HTML] Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 …

…, CA Vinter, C Nagata, KC Vollebregt, S Takeda… - The Lancet, 2022 - thelancet.com
Background Existing evidence on the effects of race and ethnicity on pregnancy outcomes is
restricted to individual studies done within specific countries and health systems. We aimed …

Fourteen babies born after round spermatid injection into human oocytes

…, S Watanabe, K Kuroda, S Takeda… - Proceedings of the …, 2015 - National Acad Sciences
During the human in vitro fertilization procedure in the assisted reproductive technology,
intracytoplasmic sperm injection is routinely used to inject a spermatozoon or a less mature …

Decidualization induces a secretome switch in perivascular niche cells of the human endometrium

…, ES Lucas, YW Chan, RP Durairaj, S Takeda… - …, 2014 - academic.oup.com
The endometrial perivascular microenvironment is rich in mesenchymal stem-like cells that
express type 1 integral membrane protein Sushi domain containing 2 (SUSD2) but the role of …

Defining definitions: a Delphi study to develop a core outcome set for conditions of severe maternal morbidity

…, P Hillemanns, R Rauskolb, S Takeda… - … Journal of Obstetrics …, 2019 - Wiley Online Library
Objective Develop a core outcome set of international consensus definitions for severe
maternal morbidities. Design Electronic Delphi study. Setting International. Population Eight …

Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve

…, IA Brosens, JJ Brosens, S Takeda… - Journal of Obstetrics …, 2012 - Wiley Online Library
Aim: The rate of oocyte decline follows a biphasic pattern, characterized by acceleration
between 32 and 38 years old. Ovarian reserve is also affected by external factors, including …

[HTML][HTML] An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis

…, SN Omura, R Nakagawa, T Togashi, SN Takeda… - Cell, 2023 - Elsevier
SpCas9 and AsCas12a are widely utilized as genome-editing tools in human cells. However,
their relatively large size poses a limitation for delivery by cargo-size-limited adeno-…