… Moreover, tumour-reactive T cells with specificity for selected neoantigens identified by
MS are detected in the patient’s tumour and peripheral blood. We conclude that direct …

Sensitive in vivo imaging technologies applicable to the clinical setting are still lacking for
adoptive T-cell–based immunotherapies, an important gap to fill if mechanisms of tumor …

Cancer immunotherapy has proven high efficacy in treating diverse cancer entities by
immune checkpoint modulation and adoptive T-cell transfer. However, patterns of treatment …

… Yusufi: conception and design of the studies together with S. Mall, AM Krackhardt, C. D'Alessandria. …
S. Reder: radiotracer iv injections of mice, small animal PET/CT scanning. R. …

… 10 μl of the mixture was electroporated with the Neon electroporation device at 1,600 V,
10 s with three pulses. The cells were transferred to 1 ml of prewarmed T-cell medium. …

… We isolated seven T-cell receptors (TCRs) from the patient’s immune repertoire recognizing
… We investigated the patient’s TCR repertoire in blood and different tumor-related tissues …

Adoptive transfer of T cells transgenic for tumor-reactive T-cell receptors (TCR) is an
attractive immunotherapeutic approach. However, clinical translation is so far limited due to …

… [49] showed back in the 1990s that adoptively transferred EBV-specific cytotoxic CD4+ and
CD8+ T lymphocytes (CTL) can reconstitute the patient’s immune responses against EBV …

… on 2 μm formalin-fixed, paraffin-embedded (FFPE) tissue slides using Maxwell® RSC
Blood DNA Kit and Maxwell® RSC RNA FFPE Kit (Promega) following the manufacturer’s …

A transthoracic echocardiogram is recommended in patients with suspected heart failure, to
improve diagnostic accuracy, and in patients with a new diagnosis of heart failure, to assess …