Biosynthesis of triacylglycerols

R Lehner, A Kuksis - Progress in lipid research, 1996 - Elsevier
All tissues and most cells are capable of some biosynthesis of triacylglycerols, although
some are better adapted for this purpose than others. Some tissues also store and secrete …

Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion

…, M Rasouli, P Martres, DE Vance, R Lehner - The FASEB …, 2003 - Wiley Online Library
The presence of elevated circulating triacylglycerol (TG)‐rich very low density lipoprotein (VLDL)
and apolipoprotein B‐100 (apoB‐100) levels represents an independent risk factor for …

Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology

Q Liu, RMP Siloto, R Lehner, SJ Stone… - Progress in lipid …, 2012 - Elsevier
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

[PDF][PDF] Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis

…, G Valle, M Giacomello, AD Quiroga, R Lehner… - Cell reports, 2021 - cell.com
Contacts between organelles create microdomains that play major roles in regulating key
intracellular activities and signaling pathways, but whether they also regulate systemic …

[HTML][HTML] Triacylglycerol synthesis by an sn-1, 2 (2, 3)-diacylglycerol transacylase from rat intestinal microsomes.

R Lehner, A Kuksis - Journal of Biological Chemistry, 1993 - Elsevier
A membrane-associated sn-1,2(2,3)-diacylglycerol transacylase activity was purified 550-fold
from the microsomes of rat intestinal villus cells. The enzyme was solubilized with the …

Phonocardiogram signal analysis: a review.

RM Rangayyan, RJ Lehner - Critical reviews in biomedical …, 1987 - europepmc.org
Many disease of the heart cause changes in heart sounds and additional murmurs before
other signs and symptoms appear. Hence, heart sound analysis by auscultation is the primary …

Techniques to measure lipase and esterase activity in vitro

D Gilham, R Lehner - Methods, 2005 - Elsevier
Lipases and esterases constitute a large category of enzymes. They are ubiquitous in nature,
found in bacteria, fungi, and animals. The family members address a wide variety of …

Carboxylesterases in lipid metabolism: from mouse to human

J Lian, R Nelson, R Lehner - Protein & cell, 2018 - academic.oup.com
Mammalian carboxylesterases hydrolyze a wide range of xenobiotic and endogenous
compounds, including lipid esters. Physiological functions of carboxylesterases in lipid …

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

…, JS Jaswal, MN Sack, R Lehner… - Cardiovascular …, 2014 - academic.oup.com
Aims Lysine acetylation is a novel post-translational pathway that regulates the activities of
enzymes involved in both fatty acid and glucose metabolism. We examined whether lysine …

[HTML][HTML] Subcutaneous adiposity is an independent predictor of mortality in cancer patients

M Ebadi, L Martin, S Ghosh, CJ Field, R Lehner… - British journal of …, 2017 - nature.com
Background: Prognostic significance of adiposity, at the time of cancer diagnosis, on survival
is not clear. Body mass index (kg m− 2) does not provide an appropriate assessment of …