[HTML][HTML] ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

…, H Schultheis, K Klee, A Petrova, R Wiegandt… - Nature …, 2020 - nature.com
While footprinting analysis of ATAC-seq data can theoretically enable investigation of
transcription factor (TF) binding, the lack of a computational tool able to conduct different levels of …

multicrispr: gRNA design for prime editing and parallel targeting of thousands of targets

AM Bhagwat, J Graumann, R Wiegandt… - Life science …, 2020 - life-science-alliance.org
Targeting the coding genome to introduce nucleotide deletions/insertions via the CRISPR/Cas9
technology has become a standard procedure. It has quickly spawned a multitude of …

WIlsON: web-based interactive omics visualization

…, C Kuenne, J Preussner, R Wiegandt… - …, 2019 - academic.oup.com
Motivation High throughput (HT) screens in the omics field are typically analyzed by automated
pipelines that generate static visualizations and comprehensive spreadsheet data for …

Beyond accessibility: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

…, H Schultheis, K Klee, A Petrova, R Wiegandt… - Biorxiv, 2019 - biorxiv.org
While footprinting analysis of ATAC-seq data can theoretically enable investigation of
transcription factor (TF) binding, the lack of a computational tool able to conduct different levels of …

[HTML][HTML] NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods

…, G Larson, J Nilsson, B Meyer, A Wiegandt… - Molecular & Cellular …, 2020 - ASBMB
Glycosylation is a topic of intense current interest in the development of biopharmaceuticals
because it is related to drug safety and efficacy. This work describes results of an …

Humanity and Collectivity: Nation, State, and Community

K Wiegandt, K Wiegandt - JM Coetzee's Revisions of the Human …, 2019 - Springer
In this chapter I read Slow Man, The Childhood of Jesus, and The Schooldays of Jesus as
reflections on how nationality, the state, and the community inflect notions of humanity. Slow …

Sulfatides are required for renal adaptation to chronic metabolic acidosis

…, R Koesters, R Sandhoff, H Wiegandt… - Proceedings of the …, 2013 - National Acad Sciences
Urinary ammonium excretion by the kidney is essential for renal excretion of sufficient amounts
of protons and to maintain stable blood pH. Ammonium secretion by the collecting duct …

Advanced Processing and Manufacturing Technologies for Structural and Multifunctional Materials VI

…, K Komeya, T Meguro, N Holstein, K Wiegandt… - Wiley Online Library
The Sixth International Symposium on Advanced Processing and Manufacturing Technologies
for Structural and Multifunctional Materials and Systems (APMT) was held during the 36th …

[PDF][PDF] Behavior of Autochrome Color Screen Dyes Under Anoxic Conditions

L Casella - Topics in Photographic Preservation, 2011 - academia.edu
… The initial enclosure design was modeled on the one used by Ralph Wiegandt for … tests
carried out by Ralph Wiegandt at George Eastman House (Wiegandt, personal communication). …

[HTML][HTML] Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases

A Bouscary, C Quessada, F René, M Spedding… - Seminars in Cell & …, 2021 - Elsevier
Sphingolipids are complex lipids. They play a structural role in neurons, but are also involved
in regulating cellular communication, and neuronal differentiation and maturation. There is …