[HTML][HTML] An ultrasensitive biosensor for detection of femtogram levels of the cancer antigen AGR2 using monoclonal antibody modified screen-printed gold electrodes

…, MA Mohtar, P Muller, B Vojtesek, R Krejcir… - Biosensors, 2021 - mdpi.com
The detection of cancer antigens is a major aim of cancer research in order to develop better
patient management through early disease detection. Many cancers including prostate, lung…

Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival

…, F Naji, R Nenutil, KL Ball, R Krejcir… - Life Science …, 2021 - life-science-alliance.org
Better understanding of GBM signalling networks in-vivo would help develop more physiologically
relevant ex vivo models to support therapeutic discovery. A “functional proteomics” …

[HTML][HTML] A cyclic pentamethinium salt induces cancer cell cytotoxicity through mitochondrial disintegration and metabolic collapse

R Krejcir, L Krcova, P Zatloukalova, T Briza… - International journal of …, 2019 - mdpi.com
Cancer cells preferentially utilize glycolysis for ATP production even in aerobic conditions (the
Warburg effect) and adapt mitochondrial processes to their specific needs. Recent studies …

[HTML][HTML] Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the in vitro …

…, L Hernychova, A Krejci, P Muller, R Krejcir… - Frontiers in …, 2022 - frontiersin.org
Defining dynamic protein–protein interactions in the ubiquitin conjugation reaction is a
challenging research area. Generating peptide aptamers that target components such as …

[HTML][HTML] Anticancer pentamethinium salt is a potent photosensitizer inducing mitochondrial disintegration and apoptosis upon red light illumination

R Krejcir, T Briza, M Sterba, O Simoncik… - … of Photochemistry and …, 2020 - Elsevier
Despite progress in the development and application of novel therapeutic agents, cancer
remains a major cause of death worldwide. Therefore, there is a need for new approaches to …

Mitochondrial Processes in Targeted Cancer Therapy.

R Krejčíř, D Valík, B Vojtěšek - Klinicka Onkologie: Casopis Ceske a …, 2018 - europepmc.org
Background During tumor initiation and progress, cellular functions adapt to the new needs
of the transformed cells and mitochondrial processes are also affected. Mitochondria are less …

[PDF][PDF] Dizertační práce

R Krejčíř - is.muni.cz
This is a study of the biological properties of newly synthesised pentamethinium salts with an
emphasis on salt-47, a compound that previously exhibited antitumour properties in vivo in …

The Development of a Canine Single-Chain Phage Antibody Library to Isolate Recombinant Antibodies for Use in Translational Cancer Research

…, MA Mohtar, F Zavadil-Kokas, V Hrabal, R Krejcir… - papers.ssrn.com
Synthetic monoclonal antibodies form compelling agents for the therapy of many human
diseases, including cancer. Spontaneous tumors in canine patients share important genetic, …

Assassinations in the underworld

K Geldenhuys - Servamus Community-based Safety and Security …, 2020 - journals.co.za
… Cyril Beeka and Radovan Krejcir were friends and business partners in … Radovan Krejcir's
associates have been murdered in separate incidents over the years, but Radovan Krejcir

Organised crime groups-the “mafia”, their members and money

K Geldenhuys - Servamus Community-based Safety and Security …, 2020 - journals.co.za
… Then there are highly effective, criminal networks consisting of a range of foreign criminal
actors seeking opportunities such as Radovan Krejcir and the group of Serbians who operated …