User profiles for Pieter Van Der Veken

Pieter Van der Veken

Professor of Medicinal Chemistry
Verified email at uantwerpen.be
Cited by 6632

[HTML][HTML] ClpP protease, a promising antimicrobial target

…, K Goossens, IG Salado, P Van Der Veken… - International journal of …, 2019 - mdpi.com
The caseinolytic protease proteolytic subunit (ClpP) is a serine protease playing an important
role in proteostasis of eukaryotic organelles and prokaryotic cells. Alteration of ClpP …

[HTML][HTML] Molecular imaging of apoptosis: the case of caspase-3 radiotracers

…, S Stroobants, P Van der Veken… - International Journal of …, 2021 - mdpi.com
The molecular imaging of apoptosis remains an important method for the diagnosis and
monitoring of the progression of certain diseases and the evaluation of the efficacy of anticancer …

3‐methyl‐1, 2, 3‐butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol

…, Y Gómez‐González, P Van der Veken… - Geophysical …, 2007 - Wiley Online Library
Highly oxygenated compounds assigned to be oxidation products of α‐pinene have recently
been observed in substantial concentrations in ambient aerosols. Here, we confirm the …

Hydroxydicarboxylic acids: Markers for secondary organic aerosol from the photooxidation of α-pinene

…, I Kourtchev, P Van der Veken… - Environmental …, 2007 - ACS Publications
Detailed organic analysis of fine (PM 2.5 ) rural aerosol collected during summer at K-puszta,
Hungary from a mixed deciduous/coniferous forest site shows the presence of polar …

Extended structure–activity relationship and pharmacokinetic investigation of (4-quinolinoyl) glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP)

…, K Augustyns, P Van der Veken - Journal of medicinal …, 2014 - ACS Publications
Fibroblast activation protein (FAP) is a serine protease related to dipeptidyl peptidase IV (DPPIV).
It has been convincingly linked to multiple disease states involving remodeling of the …

Selective inhibitors of fibroblast activation protein (FAP) with a (4-quinolinoyl)-glycyl-2-cyanopyrrolidine scaffold

…, K Augustyns, P Van der Veken - ACS medicinal …, 2013 - ACS Publications
Fibroblast activation protein (FAP) is a serine protease that is generally accepted to play an
important role in tumor growth and other diseases involving tissue remodeling. Currently …

Terpenylic acid and related compounds from the oxidation of α-pinene: Implications for new particle formation and growth above forests

…, R Vermeylen, P Van der Veken… - … science & technology, 2009 - ACS Publications
Novel secondary organic aerosol (SOA) products from the monoterpene α-pinene with unique
dimer-forming properties have been identified as lactone-containing terpenoic acids, ie, …

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ

…, M Lahtela-Kakkonen, P Van der Veken… - Biochemical …, 2014 - Elsevier
The transcription factor NF-κB is one of the main players involved in inflammatory responses
during which NF-κB becomes rapidly activated. However to maintain homeostasis, this NF-…

Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases

P Van der Veken, K Senten, I Kertèsz… - Journal of medicinal …, 2005 - ACS Publications
The feasibility of the fluoro-olefin function as a peptidomimetic group in inhibitors for dipeptidyl
peptidase IV and II (DPP IV and DPP II) is investigated by evaluation of N-substituted Gly-…

Novel drug discovery strategies for atherosclerosis that target necrosis and necroptosis

…, K Augustyns, P Van Der Veken… - Expert Opinion on …, 2018 - Taylor & Francis
Introduction: Formation and enlargement of a necrotic core play a pivotal role in atherogenesis.
Since the discovery of necroptosis, which is a regulated form of necrosis, prevention of …