SMAD4 loss limits the vulnerability of pancreatic cancer cells to complex I inhibition via promotion of mitophagy

…, J Stursa, L Werner, E Vlcak, P Kralova Viziova… - Oncogene, 2021 - nature.com
Pancreatic cancer is one of the deadliest forms of cancer, which is attributed to lack of
effective treatment options and drug resistance. Mitochondrial inhibitors have emerged as a …

[HTML][HTML] LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer

…, V Cutano, J Vinaixa-Forner, P Kralova Viziova… - Apoptosis, 2023 - Springer
Background LACTB was recently identified as a mitochondrial tumour suppressor that negatively
affects cancer cell proliferation by inducing cell death and/or differentiation, depending …

[HTML][HTML] Analysis of 5-azacytidine resistance models reveals a set of targetable pathways

…, A Jonášová, KS Vargová, P Králová Viziová… - Cells, 2022 - mdpi.com
The mechanisms by which myelodysplastic syndrome (MDS) cells resist the effects of
hypomethylating agents (HMA) are currently the subject of intensive research. A better …

LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug

…, V Zemlianski, Y Feng, PK Viziova… - Life Science …, 2023 - life-science-alliance.org
Epithelial–mesenchymal transition (EMT) is a cellular mechanism used by cancer cells to
acquire migratory and stemness properties. In this study, we show, through in vitro, in vivo, and …

Correction: LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug

…, V Zemlianski, Y Feng, PK Viziova… - Life Science …, 2023 - life-science-alliance.org
… , Viacheslav Zemlianski2, Yuxiong Feng3, Petra Kralova Viziova4, Andrea Hartmanova4,
Beata Malcekova1, Pavel Jakoube1,2 … Article: Cutano V, Ferreira Mendes JM, Escudeiro-Lopes …

[PDF][PDF] Analysis of 5-Azacytidine Resistance Models Reveals a Set of Targetable Pathways. Cells. 2022; 11: 223

…, A Jonášová, KS Vargová, P Králová Viziová… - 2022 - academia.edu
The mechanisms by which myelodysplastic syndrome (MDS) cells resist the effects of
hypomethylating agents (HMA) are currently the subject of intensive research. A better …