2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus

…, B Halda‐Kiss, S Hasni, PM Izmirly… - Arthritis & …, 2019 - Wiley Online Library
Objective To develop new classification criteria for systemic lupus erythematosus ( SLE )
jointly supported by the European League Against Rheumatism ( EULAR ) and the American …

[HTML][HTML] Covid-19 in immune-mediated inflammatory diseases—case series from New York

…, A Chen, R Castillo, D Yan, P Izmirly… - … England Journal of …, 2020 - Mass Medical Soc
Covid-19 in Immune-Mediated Inflammatory Diseases The authors describe patients in New
York City with known immune-mediated inflammatory disease in whom Covid-19 developed …

Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody–associated cardiac manifestations of neonatal lupus

PM Izmirly, N Costedoat-Chalumeau, CN Pisoni… - Circulation, 2012 - Am Heart Assoc
Background— A recent case-control study suggested a benefit of hydroxychloroquine (HCQ)
in lowering the risk of cardiac manifestations of neonatal lupus (cardiac-NL) in pregnancies …

Methotrexate hampers immunogenicity to BNT162b2 mRNA COVID-19 vaccine in immune-mediated inflammatory disease

…, S Adhikari, N Azar, P Rosenthal, P Izmirly… - Annals of the …, 2021 - ard.bmj.com
Objective To investigate the humoral and cellular immune response to messenger RNA (mRNA)
COVID-19 vaccines in patients with immune-mediated inflammatory diseases (IMIDs) …

Prevalence of systemic lupus erythematosus in the United States: estimates from a meta‐analysis of the Centers for Disease Control and Prevention National Lupus …

PM Izmirly, H Parton, L Wang… - Arthritis & …, 2021 - Wiley Online Library
Objective Epidemiologic data on systemic lupus erythematosus (SLE) are limited, particularly
for racial/ethnic subpopulations in the US. This meta‐analysis leveraged data from the …

Maternal and fetal factors associated with mortality and morbidity in a multi–racial/ethnic registry of anti-SSA/Ro–associated cardiac neonatal lupus

PM Izmirly, A Saxena, MY Kim, D Wang, SK Sahl… - Circulation, 2011 - Am Heart Assoc
Background— Cardiac manifestations of neonatal lupus include conduction disease and,
rarely, an isolated cardiomyopathy. This study was initiated to determine the mortality and …

Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus …

PM Izmirly, MY Kim, C Llanos, PU Le… - Annals of the …, 2010 - ard.bmj.com
Background Based on the potential involvement of Toll-like receptor (TLR) signalling in the
pathogenesis of neonatal lupus (NL), it was hypothesised that fetal exposure to …

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

…, M Kustagi, B Goilav, S Ranabothu, P Izmirly… - Nature …, 2019 - nature.com
The molecular and cellular processes that lead to renal damage and to the heterogeneity of
lupus nephritis (LN) are not well understood. We applied single-cell RNA sequencing (…

Evaluation of immune response and disease status in systemic lupus erythematosus patients following SARS–CoV‐2 vaccination

PM Izmirly, MY Kim, M Samanovic… - Arthritis & …, 2022 - Wiley Online Library
Objective To evaluate seroreactivity and disease flares after COVID‐19 vaccination in a
multiethnic/multiracial cohort of patients with systemic lupus erythematosus (SLE). Methods …

The clinical spectrum of autoimmune congenital heart block

P Brito-Zerón, PM Izmirly, M Ramos-Casals… - Nature Reviews …, 2015 - nature.com
Autoimmune congenital heart block (CHB) is an immune-mediated acquired disease that is
associated with the placental transference of maternal antibodies specific for Ro and La …