User profiles for Peter Balfe

Peter Balfe

University of Birmingham
Verified email at bham.ac.uk
Cited by 10434

Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers

P Simmonds, P Balfe, JF Peutherer, CA Ludlam… - Journal of …, 1990 - Am Soc Microbiol
In human immunodeficiency virus (HIV)-infected individuals, the proportion of circulating
mononuclear cells (PBMCs) which carry HIV provirus and the number of HIV proviral …

Neutralizing antibody response during acute and chronic hepatitis C virus infection

…, S Heyward, A Talal, P Balfe… - Proceedings of the …, 2004 - National Acad Sciences
Little is known about the role of Abs in determining the outcome of hepatitis C virus (HCV)
infection. By using infectious retroviral pseudotypes bearing HCV glycoproteins, we measured …

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

…, JC Yoon, H Alter, CM Rice, B Rehermann, P Balfe… - Gastroenterology, 2007 - Elsevier
Background & Aims: Broadly reactive neutralizing antibodies (nAbs) and multispecific T-cell
responses are generated during chronic hepatitis C virus (HCV) infection and yet fail to clear …

[PDF][PDF] Hepatitis C virus cell‐cell transmission in hepatoma cells in the presence of neutralizing antibodies

…, A Schwarz, I Desombere, GL Roels, P Balfe… - …, 2008 - Wiley Online Library
Hepatitis C virus (HCV) infection of Huh‐7.5 hepatoma cells results in focal areas of infection
where transmission is potentiated by cell‐cell contact. To define route(s) of transmission, …

Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission

…, TL Tellinghuisen, F Wong-Staal, P Balfe… - Journal of …, 2011 - Am Soc Microbiol
Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent
transmission. In this study we use a novel infectious coculture system to examine these …

[HTML][HTML] Claudin association with CD81 defines hepatitis C virus entry

…, K McCaffrey, S Young, H Drummer, P Balfe… - Journal of Biological …, 2010 - ASBMB
Viruses initiate infection by attaching to molecules or receptors at the cell surface. Hepatitis
C virus (HCV) enters cells via a multistep process involving tetraspanin CD81, scavenger …

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

…, KS Kim, IA Romero, C Jopling, S Morgello, P Balfe… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease
and is associated with a variety of extrahepatic syndromes, including central nervous …

CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry

…, HK Deng, SG Hubscher, JH Han, P Balfe… - Journal of …, 2008 - Am Soc Microbiol
Hepatitis C virus (HCV) is an enveloped positive-stranded RNA hepatotropic virus. HCV
pseudoparticles infect liver-derived cells, supporting a model in which liver-specific molecules …

Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1

P Simmonds, P Balfe, CA Ludlam, JO Bishop… - Journal of …, 1990 - Am Soc Microbiol
Nucleotide sequences in three hypervariable regions of the human immunodeficiency virus
type 1 (HIV-1) env gene were obtained by sequencing provirus present in peripheral blood …

Hepatitis C virus induces CD81 and claudin-1 endocytosis

…, TF Baumert, JZ Rappoport, P Balfe… - Journal of …, 2012 - Am Soc Microbiol
Hepatitis C virus (HCV) leads to progressive liver disease and hepatocellular carcinoma.
Current treatments are only partially effective, and new therapies targeting viral and host …