User profiles for Paul Kellam

Paul Kellam

Imperial College London & RQ Biotechnology Ltd
Verified email at imperial.ac.uk
Cited by 28519

[HTML][HTML] Hospital outbreak of Middle East respiratory syndrome coronavirus

…, M Cotten, SJ Watson, P Kellam… - … England Journal of …, 2013 - Mass Medical Soc
Background In September 2012, the World Health Organization reported the first cases of
pneumonia caused by the novel Middle East respiratory syndrome coronavirus (MERS-CoV). …

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

N Dupin, C Fisher, P Kellam, S Ariad… - Proceedings of the …, 1999 - National Acad Sciences
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi’s
sarcoma (KS), multicentric Castleman’s disease (MCD), and primary effusion lymphoma (…

The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection

P Kellam, W Barclay - Journal of General Virology, 2020 - microbiologyresearch.org
SARS-CoV-2 is a novel coronavirus that is the causative agent of coronavirus infectious disease
2019 (COVID-19). As of 17 April 2020, it has infected 2 114 269 people, resulting in 145 …

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

…, DD Ho, KYA Huang, J Ingraham, W Jiang, P Kellam… - Science, 2021 - science.org
Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and
mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. …

HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8–positive plasmablastic lymphoma

N Dupin, TL Diss, P Kellam, M Tulliez… - Blood, The Journal …, 2000 - ashpublications.org
Castleman disease (CD) is a lymphoproliferative disorder of unknown etiology that is
associated with the development of secondary tumors, including B-cell lymphoma. Human …

[HTML][HTML] Antibody response to SARS-CoV-2 infection in humans: A systematic review

…, S Rigby, SV Williams, WH Bermingham, P Kellam… - PloS one, 2020 - journals.plos.org
Background Progress in characterising the humoral immune response to Severe Acute
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist. …

The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma–E2F pathway and with the oncogene Hras transforms primary rat …

SA Radkov, P Kellam, C Boshoff - Nature medicine, 2000 - nature.com
Kaposi sarcoma-associated herpesvirus (KSHV) is involved in the etiopathogenesis of
Kaposi sarcoma and certain lymphoproliferative disorders. Open reading frame (ORF) 73 …

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

…, JE Daigle, S Hughes, P Kellam… - Genes & …, 2007 - genesdev.cshlp.org
LEDGF/p75 directly interacts with lentiviral integrase proteins and can modulate their
enzymatic activities and chromosomal association. A novel genetic knockout model was …

Scientific consensus on the COVID-19 pandemic: we need to act now

…, A Hamdy, WP Hanage, EB Hodcroft, Z Hyde, P Kellam… - The Lancet, 2020 - thelancet.com
Next Article Redevelopment and validation of the SYNTAX score II to individualise decision
making between percutaneous and surgical revascularisation in patients with complex …

Poxvirus genomes: a phylogenetic analysis

C Gubser, S Hué, P Kellam… - Journal of General …, 2004 - microbiologyresearch.org
The evolutionary relationships of 26 sequenced members of the poxvirus family have been
investigated by comparing their genome organization and gene content and by using DNA …