Tuberoinfundibular dopamine (TIDA) neurons are the central regulators of prolactin (PRL)
secretion. Their extensive functional plasticity allows a change from low PRL secretion in the …

Recent advances in tridimensional (3D) tissue imaging have considerably enriched our
view of the pituitary gland and its development. Whereas traditional histology of the pituitary …

All higher life forms critically depend on hormones being rhythmically released by the
anterior pituitary. The proper functioning of this master gland is dynamically controlled by a …

The discoveries of novel functional adaptations of the hypothalamus and anterior pituitary
gland for physiological regulation have transformed our understanding of their interaction. The …

A compound's intratumoural distribution is an important determinant for the effectiveness of
molecular therapy or imaging. Antibodies (Abs), though often used in the design of targeted …

Pituitary growth hormone (GH)-secreting cells regulate growth and metabolism in animals
and humans. To secrete highly ordered GH pulses (up to 1,000-fold rise in hormone levels in …

Experience-dependent plasticity of cell and tissue function is critical for survival by allowing
organisms to dynamically adjust physiological processes in response to changing or harsh …

To maintain homeostasis, hypothalamic neurons in the arcuate nucleus must dynamically
sense and integrate a multitude of peripheral signals. Blood-borne molecules must therefore …

This review summarizes the current understanding of the development of the neuroendocrine
gonadotropin‐releasing hormone (GnRH) system, including discussion on open questions …

Sox2 + adult mouse pituitary cells can self-renew and terminally differentiate in vitro, but their
physiological role in vivo and possible contribution to oncogenesis remain largely unknown…