During progression of atherosclerosis, myeloid cells destabilize lipid-rich plaques in the
arterial wall and cause their rupture, thus triggering myocardial infarction and stroke. Survivors …

Nanocrystalline silicon carbide (SiC) thin films were deposited by plasma enhanced chemical
vapor deposition technique at different deposition temperatures (T d ) ranging from 80 to …

Excessive and prolonged activity of inflammatory monocytes is a hallmark of many diseases
with an inflammatory component. In such conditions, precise targeting of these cells could …

Exposure to psychosocial stress is a risk factor for many diseases, including atherosclerosis
1 , 2 . Although incompletely understood, interaction between the psyche and the immune …

Dysfunctional endothelium contributes to more diseases than any other tissue in the body.
Small interfering RNAs (siRNAs) can help in the study and treatment of endothelial cells in …

Rationale: Macrophages populate the steady-state myocardium. Previously, all macrophages
were thought to arise from monocytes; however, it emerged that, in several organs, tissue-…

Monocytes (Mo) and macrophages (MΦ) are emerging therapeutic targets in malignant,
cardiovascular, and autoimmune disorders. Targeting of Mo/MΦ and their effector functions …

Objectives : The aim of this study was to explore post–myocardial infarction (MI) myocardial
inflammation. Background : Innate immune cells are centrally involved in infarct healing and …

Background— Exaggerated and prolonged inflammation after myocardial infarction (MI)
accelerates left ventricular remodeling. Inflammatory pathways may present a therapeutic target …

Objectives : The aim of this study was to test whether silencing of the transcription factor
interferon regulatory factor 5 (IRF5) in cardiac macrophages improves infarct healing and …