User profiles for Paola Cusumano

Paola Cusumano

Università di Padova
Verified email at unipd.it
Cited by 772

Peptidergic clock neurons in Drosophila: Ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons

…, T Yoishii, H Dircksen, P Cusumano… - Journal of …, 2009 - Wiley Online Library
About 150 clock neurons are clustered in different groups in the brain of Drosophila. Among
these clock neurons, some pigment‐dispersing factor (PDF)‐positive and PDF‐negative …

[HTML][HTML] Light Activates Output from Evening Neurons and Inhibits Output from Morning Neurons in the Drosophila Circadian Clock

M Picot, P Cusumano, A Klarsfeld, R Ueda… - PLoS biology, 2007 - journals.plos.org
Animal circadian clocks are based on multiple oscillators whose interactions allow the daily
control of complex behaviors. The Drosophila brain contains a circadian clock that controls …

modulated visual inputs and cryptochrome define diurnal behavior in Drosophila

P Cusumano, A Klarsfeld, E Chélot, M Picot… - Nature …, 2009 - nature.com
Morning and evening circadian oscillators control the bimodal activity of Drosophila in light-dark
cycles. The lateral neurons evening oscillator (LN-EO) is important for promoting diurnal …

[HTML][HTML] Peptidergic signaling from clock neurons regulates reproductive dormancy in Drosophila melanogaster

D Nagy, P Cusumano, G Andreatta, AM Anduaga… - PLoS …, 2019 - journals.plos.org
With the approach of winter, many insects switch to an alternative protective developmental
program called diapause. Drosophila melanogaster females overwinter as adults by …

[HTML][HTML] Modulation of miR-210 alters phasing of circadian locomotor activity and impairs projections of PDF clock neurons in Drosophila melanogaster

P Cusumano, A Biscontin, F Sandrelli… - PLoS …, 2018 - journals.plos.org
Single microRNAs are usually associated with hundreds of putative target genes that can
influence multiple phenotypic traits in Drosophila, ranging from development to behaviour. We …

Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction

…, L Locatello, C Da Rè, P Cusumano… - Life Science …, 2019 - life-science-alliance.org
Aberrant mitochondrial dynamics disrupts mitochondrial function and contributes to disease
conditions. A targeted RNA interference screen for deubiquitinating enzymes (DUBs) …

[HTML][HTML] Better sleep at night: how light influences sleep in Drosophila

GM Mazzotta, M Damulewicz, P Cusumano - Frontiers in Physiology, 2020 - frontiersin.org
Sleep-like states have been described in Drosophila and the mechanisms and factors that
generate and define sleep-wake profiles in this model organism are being thoroughly …

[HTML][HTML] Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock in Drosophila melanogaster

M Schlichting, D Rieger, P Cusumano… - Frontiers in molecular …, 2018 - frontiersin.org
Cryptochromes (CRYs) are a class of flavoproteins that sense blue light. In animals, CRYs
are expressed in the eyes and in the clock neurons that control sleep/wake cycles and are …

[HTML][HTML] Identifying pathways modulating sleep duration: from genomics to transcriptomics

KV Allebrandt, M Teder-Laving, P Cusumano… - Scientific reports, 2017 - nature.com
Recognizing that insights into the modulation of sleep duration can emerge by exploring the
functional relationships among genes, we used this strategy to explore the genome-wide …

[HTML][HTML] Calmodulin Enhances Cryptochrome Binding to INAD in Drosophila Photoreceptors

…, G Minervini, M Damulewicz, P Cusumano… - Frontiers in Molecular …, 2018 - frontiersin.org
Light is the main environmental stimulus that synchronizes the endogenous timekeeping
systems in most terrestrial organisms. Drosophila cryptochrome (dCRY) is a light-responsive …