User profiles for Ofer Rog
Ofer RogUniversity of Utah Verified email at utah.edu Cited by 1306 |
The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors
O Rog, S Köhler, AF Dernburg - Elife, 2017 - elifesciences.org
10.7554/eLife.21455.001 The synaptonemal complex (SC) is a polymer that spans ~100 nm
between paired homologous chromosomes during meiosis. Its striated, periodic …
between paired homologous chromosomes during meiosis. Its striated, periodic …
Let's get physical–mechanisms of crossover interference
L von Diezmann, O Rog - Journal of cell science, 2021 - journals.biologists.com
The formation of crossovers between homologous chromosomes is key to sexual reproduction.
In most species, crossovers are spaced further apart than would be expected if they …
In most species, crossovers are spaced further apart than would be expected if they …
Semi-conservative DNA replication through telomeres requires Taz1
Telomere replication is achieved through the combined action of the conventional DNA
replication machinery and the reverse transcriptase, telomerase. Telomere-binding proteins …
replication machinery and the reverse transcriptase, telomerase. Telomere-binding proteins …
[PDF][PDF] Direct visualization reveals kinetics of meiotic chromosome synapsis
O Rog, AF Dernburg - Cell reports, 2015 - cell.com
The synaptonemal complex (SC) is a conserved protein complex that stabilizes interactions
along homologous chromosomes (homologs) during meiosis. The SC regulates genetic …
along homologous chromosomes (homologs) during meiosis. The SC regulates genetic …
Identification of novel synaptonemal complex components in C. elegans
The synaptonemal complex (SC) is a tripartite protein scaffold that forms between homologous
chromosomes during meiosis. Although the SC is essential for stable homologue pairing …
chromosomes during meiosis. Although the SC is essential for stable homologue pairing …
Chromosome pairing and synapsis during Caenorhabditis elegans meiosis
O Rog, AF Dernburg - Current opinion in cell biology, 2013 - Elsevier
Meiosis is the specialized cell division cycle that produces haploid gametes to enable sexual
reproduction. Reduction of chromosome number by half requires elaborate chromosome …
reproduction. Reduction of chromosome number by half requires elaborate chromosome …
[HTML][HTML] Building the synaptonemal complex: Molecular interactions between the axis and the central region
SG Gordon, O Rog - PLoS Genetics, 2023 - journals.plos.org
The successful delivery of genetic material to gametes requires tightly regulated interactions
between the parental chromosomes. Central to this regulation is a conserved chromosomal …
between the parental chromosomes. Central to this regulation is a conserved chromosomal …
The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins
Proteins of the HORMA domain family play central, but poorly understood, roles in
chromosome organization and dynamics during meiosis. In Caenorhabditis elegans, four such …
chromosome organization and dynamics during meiosis. In Caenorhabditis elegans, four such …
Dynein-dependent processive chromosome motions promote homologous pairing in C. elegans meiosis
Meiotic chromosome segregation requires homologue pairing, synapsis, and crossover
recombination, which occur during meiotic prophase. Telomere-led chromosome motion has …
recombination, which occur during meiotic prophase. Telomere-led chromosome motion has …
[PDF][PDF] Meiotic sister chromatid exchanges are rare in C. elegans
DE Almanzar, SG Gordon, O Rog - Current Biology, 2021 - cell.com
Sexual reproduction shuffles the parental genomes to generate new genetic combinations.
To achieve that, the genome is subjected to numerous double-strand breaks, the repair of …
To achieve that, the genome is subjected to numerous double-strand breaks, the repair of …