Many pathological states characterized by muscle atrophy (eg, sepsis, cachexia, starvation,
metabolic acidosis and severe insulinopenia) are associated with an increase in circulating …

Glucocorticoid-induced muscle atrophy is characterized by fast-twitch or type II muscle fiber
atrophy illustrated by decreased fiber cross-sectional area and reduced myofibrillar protein …

… (Reprinted from Schakman et al. [10] with permission from The Endocrine Society. © 2005, …
(Reprinted from Schakman et al. [10] with permission from The Endocrine Society. © 2005, …

Glucocorticoids mediate muscle atrophy in many catabolic states. Myostatin expression, a
negative regulator of muscle growth, is increased by glucocorticoids and myostatin …

Follistatin (FS) inhibits several members of the TGF-β superfamily, including myostatin (Mstn),
a negative regulator of muscle growth. Mstn inhibition by FS represents a potential …

The gut microbiota has recently been proposed as a novel component in the regulation of
host homeostasis and immunity. We have assessed for the first time the role of the gut …

… pathways can compensate deficient MPC activity, reduced contributions of glucose and
lactate to mitochondrial pyruvate is sufficient to profoundly alter OXPHOS and locally increase O …

… The primary emulsion (W 1 /O) was recirculated through the system and was … 1 /O/W 2 ),
which was further homogenized by circulation through the system for another 30 s. The W 1 /O/W …

Skeletal muscle contraction is reputed not to depend on extracellular Ca 2+ . Indeed, stricto
sensu , excitation-contraction coupling does not necessitate entry of Ca 2+ . However, we …

Background The proinflammatory cytokine interleukin-1β (IL-1β) is overexpressed in Alzheimer
disease (AD) as a key regulator of neuroinflammation. Amyloid-β (Aβ) peptide triggers …